Action potential broadening in a presynaptic channelopathy

Episodic ataxia type 1 is caused by mutations in the potassium channel Kv1.1, which is found in cerebellar basket cells. Here, the authors use electrophysiology techniques to characterize these mutant channels, and observe that the changes result in decreased spontaneous Purkinje cell firing with no...

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Autores principales: Rahima Begum, Yamina Bakiri, Kirill E. Volynski, Dimitri M. Kullmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/34260921036645c1afdf57d613180339
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