Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes.

The activation of the transcription factor NF-κB leads to changes in expression of many genes in pancreatic β-cells. However, the role of NF-κB activation in islet transplantation has not been fully elucidated. The aim of the present study was to investigate whether the state of NF-κB activation wou...

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Autores principales: Aileen J F King, Yongjing Guo, Dongsheng Cai, Jennifer Hollister-Lock, Brooke Morris, Alison Salvatori, John A Corbett, Susan Bonner-Weir, Steven E Shoelson, Gordon C Weir
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/342a868255eb493da4e9de391aaf79a3
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