Patch test of dental materials in Oral Lichen Planus with considering the role of saliva

Abstract Lichen planus is the most common skin disease that affects the oral mucosa. Oral Lichen Planus is a T-cell-mediated autoimmune disorder. In the current study, for the first time, an oral cavity condition in skin patch tests with adding saliva is simulated. In addition, the patch results are...

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Autores principales:	Farzaneh Agha-Hosseini, Elahe Gholamrezayi, Mahdieh-Sadat Moosavi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/342ab05ebaca4230b716d7470f46b830
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spelling	oai:doaj.org-article:342ab05ebaca4230b716d7470f46b8302021-12-02T15:51:12ZPatch test of dental materials in Oral Lichen Planus with considering the role of saliva10.1038/s41598-021-87778-82045-2322https://doaj.org/article/342ab05ebaca4230b716d7470f46b8302021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87778-8https://doaj.org/toc/2045-2322Abstract Lichen planus is the most common skin disease that affects the oral mucosa. Oral Lichen Planus is a T-cell-mediated autoimmune disorder. In the current study, for the first time, an oral cavity condition in skin patch tests with adding saliva is simulated. In addition, the patch results are compared with healthy subjects. Forty-one OLP patients and 63 healthy subjects were enrolled in the study. All participants were provided with patch tests, including allergens, in combination with saliva in chambers. Allergens from the European baseline (standard) series selected according to the most prevalent positive results in the previous study were applied. Positive results of Mercury and Cobalt tests were significantly higher in the case group. In this study, the differentiation of patients with lichen planus and lichenoid was identified according to the Van der Meij & Van der Waal criteria. The patch test was conducted for healthy individuals as well. The most important of all was the use of patients' saliva in the patch test, done for the first time in this field. In the case of OLP, a patch test can help identify positive reactions to dental materials; thus, the replacement of dental restorations may be needed.Farzaneh Agha-HosseiniElahe GholamrezayiMahdieh-Sadat MoosaviNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Farzaneh Agha-Hosseini Elahe Gholamrezayi Mahdieh-Sadat Moosavi Patch test of dental materials in Oral Lichen Planus with considering the role of saliva
description	Abstract Lichen planus is the most common skin disease that affects the oral mucosa. Oral Lichen Planus is a T-cell-mediated autoimmune disorder. In the current study, for the first time, an oral cavity condition in skin patch tests with adding saliva is simulated. In addition, the patch results are compared with healthy subjects. Forty-one OLP patients and 63 healthy subjects were enrolled in the study. All participants were provided with patch tests, including allergens, in combination with saliva in chambers. Allergens from the European baseline (standard) series selected according to the most prevalent positive results in the previous study were applied. Positive results of Mercury and Cobalt tests were significantly higher in the case group. In this study, the differentiation of patients with lichen planus and lichenoid was identified according to the Van der Meij & Van der Waal criteria. The patch test was conducted for healthy individuals as well. The most important of all was the use of patients' saliva in the patch test, done for the first time in this field. In the case of OLP, a patch test can help identify positive reactions to dental materials; thus, the replacement of dental restorations may be needed.
format	article
author	Farzaneh Agha-Hosseini Elahe Gholamrezayi Mahdieh-Sadat Moosavi
author_facet	Farzaneh Agha-Hosseini Elahe Gholamrezayi Mahdieh-Sadat Moosavi
author_sort	Farzaneh Agha-Hosseini
title	Patch test of dental materials in Oral Lichen Planus with considering the role of saliva
title_short	Patch test of dental materials in Oral Lichen Planus with considering the role of saliva
title_full	Patch test of dental materials in Oral Lichen Planus with considering the role of saliva
title_fullStr	Patch test of dental materials in Oral Lichen Planus with considering the role of saliva
title_full_unstemmed	Patch test of dental materials in Oral Lichen Planus with considering the role of saliva
title_sort	patch test of dental materials in oral lichen planus with considering the role of saliva
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/342ab05ebaca4230b716d7470f46b830
work_keys_str_mv	AT farzanehaghahosseini patchtestofdentalmaterialsinorallichenplanuswithconsideringtheroleofsaliva AT elahegholamrezayi patchtestofdentalmaterialsinorallichenplanuswithconsideringtheroleofsaliva AT mahdiehsadatmoosavi patchtestofdentalmaterialsinorallichenplanuswithconsideringtheroleofsaliva
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Patch test of dental materials in Oral Lichen Planus with considering the role of saliva

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