Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results

This paper presents a new field-effect sensor called open-gate junction gate field-effect transistor (OG-JFET) for biosensing applications. The OG-JFET consists of a p-type channel on top of an n-type layer in which the p-type serves as the sensing conductive layer between two ohmic contacted source...

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Autores principales:	Abbas Panahi, Deniz Sadighbayan, Ebrahim Ghafar-Zadeh
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	field-effect transistor (FET) biosensor DNA sensor oral neutrophil ISFET BioFET Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/34315c6ca7624c749de80a1e33692ed5
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spelling	oai:doaj.org-article:34315c6ca7624c749de80a1e33692ed52021-11-25T18:56:52ZElectronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results10.3390/s212274911424-8220https://doaj.org/article/34315c6ca7624c749de80a1e33692ed52021-11-01T00:00:00Zhttps://www.mdpi.com/1424-8220/21/22/7491https://doaj.org/toc/1424-8220This paper presents a new field-effect sensor called open-gate junction gate field-effect transistor (OG-JFET) for biosensing applications. The OG-JFET consists of a p-type channel on top of an n-type layer in which the p-type serves as the sensing conductive layer between two ohmic contacted sources and drain electrodes. The structure is novel as it is based on a junction field-effect transistor with a subtle difference in that the top gate (n-type contact) has been removed to open the space for introducing the biomaterial and solution. The channel can be controlled through a back gate, enabling the sensor’s operation without a bulky electrode inside the solution. In this research, in order to demonstrate the sensor’s functionality for chemical and biosensing, we tested OG-JFET with varying pH solutions, cell adhesion (human oral neutrophils), human exhalation, and DNA molecules. Moreover, the sensor was simulated with COMSOL Multiphysics to gain insight into the sensor operation and its ion-sensitive capability. The complete simulation procedures and the physics of pH modeling is presented here, being numerically solved in COMSOL Multiphysics software. The outcome of the current study puts forward OG-JFET as a new platform for biosensing applications.Abbas PanahiDeniz SadighbayanEbrahim Ghafar-ZadehMDPI AGarticlefield-effect transistor (FET)biosensorDNA sensororal neutrophilISFETBioFETChemical technologyTP1-1185ENSensors, Vol 21, Iss 7491, p 7491 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	field-effect transistor (FET) biosensor DNA sensor oral neutrophil ISFET BioFET Chemical technology TP1-1185
spellingShingle	field-effect transistor (FET) biosensor DNA sensor oral neutrophil ISFET BioFET Chemical technology TP1-1185 Abbas Panahi Deniz Sadighbayan Ebrahim Ghafar-Zadeh Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results
description	This paper presents a new field-effect sensor called open-gate junction gate field-effect transistor (OG-JFET) for biosensing applications. The OG-JFET consists of a p-type channel on top of an n-type layer in which the p-type serves as the sensing conductive layer between two ohmic contacted sources and drain electrodes. The structure is novel as it is based on a junction field-effect transistor with a subtle difference in that the top gate (n-type contact) has been removed to open the space for introducing the biomaterial and solution. The channel can be controlled through a back gate, enabling the sensor’s operation without a bulky electrode inside the solution. In this research, in order to demonstrate the sensor’s functionality for chemical and biosensing, we tested OG-JFET with varying pH solutions, cell adhesion (human oral neutrophils), human exhalation, and DNA molecules. Moreover, the sensor was simulated with COMSOL Multiphysics to gain insight into the sensor operation and its ion-sensitive capability. The complete simulation procedures and the physics of pH modeling is presented here, being numerically solved in COMSOL Multiphysics software. The outcome of the current study puts forward OG-JFET as a new platform for biosensing applications.
format	article
author	Abbas Panahi Deniz Sadighbayan Ebrahim Ghafar-Zadeh
author_facet	Abbas Panahi Deniz Sadighbayan Ebrahim Ghafar-Zadeh
author_sort	Abbas Panahi
title	Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results
title_short	Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results
title_full	Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results
title_fullStr	Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results
title_full_unstemmed	Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results
title_sort	electronic sensing platform (esp) based on open-gate junction field-effect transistor (og-jfet) for life science applications: design, modeling and experimental results
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/34315c6ca7624c749de80a1e33692ed5
work_keys_str_mv	AT abbaspanahi electronicsensingplatformespbasedonopengatejunctionfieldeffecttransistorogjfetforlifescienceapplicationsdesignmodelingandexperimentalresults AT denizsadighbayan electronicsensingplatformespbasedonopengatejunctionfieldeffecttransistorogjfetforlifescienceapplicationsdesignmodelingandexperimentalresults AT ebrahimghafarzadeh electronicsensingplatformespbasedonopengatejunctionfieldeffecttransistorogjfetforlifescienceapplicationsdesignmodelingandexperimentalresults
_version_	1718410515096535040

Electronic Sensing Platform (ESP) Based on Open-Gate Junction Field-Effect Transistor (OG-JFET) for Life Science Applications: Design, Modeling and Experimental Results

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