A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors

Gram-negative bacteria deliver effectors via the type VI secretion system (T6SS) to outcompete their rivals. Here, Fridman et al. present an approach to identify T6SS effectors encoded in bacterial genomes without prior knowledge of their domain content or genetic neighbourhood, and identify a new f...

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Autores principales:	Chaya M. Fridman, Kinga Keppel, Motti Gerlic, Eran Bosis, Dor Salomon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3444dc408e5e4d908b3fa4cee097bc38
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spelling	oai:doaj.org-article:3444dc408e5e4d908b3fa4cee097bc382021-12-02T16:49:28ZA comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors10.1038/s41467-020-14951-42041-1723https://doaj.org/article/3444dc408e5e4d908b3fa4cee097bc382020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14951-4https://doaj.org/toc/2041-1723Gram-negative bacteria deliver effectors via the type VI secretion system (T6SS) to outcompete their rivals. Here, Fridman et al. present an approach to identify T6SS effectors encoded in bacterial genomes without prior knowledge of their domain content or genetic neighbourhood, and identify a new family of membrane-disrupting effectors.Chaya M. FridmanKinga KeppelMotti GerlicEran BosisDor SalomonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chaya M. Fridman Kinga Keppel Motti Gerlic Eran Bosis Dor Salomon A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
description	Gram-negative bacteria deliver effectors via the type VI secretion system (T6SS) to outcompete their rivals. Here, Fridman et al. present an approach to identify T6SS effectors encoded in bacterial genomes without prior knowledge of their domain content or genetic neighbourhood, and identify a new family of membrane-disrupting effectors.
format	article
author	Chaya M. Fridman Kinga Keppel Motti Gerlic Eran Bosis Dor Salomon
author_facet	Chaya M. Fridman Kinga Keppel Motti Gerlic Eran Bosis Dor Salomon
author_sort	Chaya M. Fridman
title	A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
title_short	A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
title_full	A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
title_fullStr	A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
title_full_unstemmed	A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
title_sort	comparative genomics methodology reveals a widespread family of membrane-disrupting t6ss effectors
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3444dc408e5e4d908b3fa4cee097bc38
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A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors

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