Target specific functions of EPL interneurons in olfactory circuits

The precise cell-type specific role of inhibitory interneurons in regulating sensory responses in the olfactory bulb is not known. Here, the authors report that removing GABAergic inhibition from one layer differentially affects response dynamics of the two main output cell types and changes odor mi...

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Autores principales:	Gary Liu, Emmanouil Froudarakis, Jay M. Patel, Mikhail Y. Kochukov, Brandon Pekarek, Patrick J. Hunt, Mayuri Patel, Kevin Ung, Chia-Hsuan Fu, Juyeong Jo, Hyun-Kyoung Lee, Andreas S. Tolias, Benjamin R. Arenkiel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3447ca4da8274a90a90b01e142722f89
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spelling	oai:doaj.org-article:3447ca4da8274a90a90b01e142722f892021-12-02T14:39:55ZTarget specific functions of EPL interneurons in olfactory circuits10.1038/s41467-019-11354-y2041-1723https://doaj.org/article/3447ca4da8274a90a90b01e142722f892019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11354-yhttps://doaj.org/toc/2041-1723The precise cell-type specific role of inhibitory interneurons in regulating sensory responses in the olfactory bulb is not known. Here, the authors report that removing GABAergic inhibition from one layer differentially affects response dynamics of the two main output cell types and changes odor mixture processing.Gary LiuEmmanouil FroudarakisJay M. PatelMikhail Y. KochukovBrandon PekarekPatrick J. HuntMayuri PatelKevin UngChia-Hsuan FuJuyeong JoHyun-Kyoung LeeAndreas S. ToliasBenjamin R. ArenkielNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gary Liu Emmanouil Froudarakis Jay M. Patel Mikhail Y. Kochukov Brandon Pekarek Patrick J. Hunt Mayuri Patel Kevin Ung Chia-Hsuan Fu Juyeong Jo Hyun-Kyoung Lee Andreas S. Tolias Benjamin R. Arenkiel Target specific functions of EPL interneurons in olfactory circuits
description	The precise cell-type specific role of inhibitory interneurons in regulating sensory responses in the olfactory bulb is not known. Here, the authors report that removing GABAergic inhibition from one layer differentially affects response dynamics of the two main output cell types and changes odor mixture processing.
format	article
author	Gary Liu Emmanouil Froudarakis Jay M. Patel Mikhail Y. Kochukov Brandon Pekarek Patrick J. Hunt Mayuri Patel Kevin Ung Chia-Hsuan Fu Juyeong Jo Hyun-Kyoung Lee Andreas S. Tolias Benjamin R. Arenkiel
author_facet	Gary Liu Emmanouil Froudarakis Jay M. Patel Mikhail Y. Kochukov Brandon Pekarek Patrick J. Hunt Mayuri Patel Kevin Ung Chia-Hsuan Fu Juyeong Jo Hyun-Kyoung Lee Andreas S. Tolias Benjamin R. Arenkiel
author_sort	Gary Liu
title	Target specific functions of EPL interneurons in olfactory circuits
title_short	Target specific functions of EPL interneurons in olfactory circuits
title_full	Target specific functions of EPL interneurons in olfactory circuits
title_fullStr	Target specific functions of EPL interneurons in olfactory circuits
title_full_unstemmed	Target specific functions of EPL interneurons in olfactory circuits
title_sort	target specific functions of epl interneurons in olfactory circuits
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3447ca4da8274a90a90b01e142722f89
work_keys_str_mv	AT garyliu targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT emmanouilfroudarakis targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT jaympatel targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT mikhailykochukov targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT brandonpekarek targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT patrickjhunt targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT mayuripatel targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT kevinung targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT chiahsuanfu targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT juyeongjo targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT hyunkyounglee targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT andreasstolias targetspecificfunctionsofeplinterneuronsinolfactorycircuits AT benjaminrarenkiel targetspecificfunctionsofeplinterneuronsinolfactorycircuits
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Target specific functions of EPL interneurons in olfactory circuits

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