PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION

The article presents results of studies concerning subрopulations of peripheral blood lymphocyte in the patients at early stages of age-related macular degeneration (AMD), being compared with healthy elderly persons (risk group for AMD), and young adults without ophthalmological problems. We have re...

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Autores principales:	N. V. Balatskaya, E. A. Eremeeva, O. S. Slepova, M. V. Ryabina, I. G. Kulikova, E. S. Sorozhkina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2015
Materias:	lymphocytes subpopulation profile blood macular degeneration age-related Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/34487c0c76a84b008c8578c6e7b0a5b6
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spelling	oai:doaj.org-article:34487c0c76a84b008c8578c6e7b0a5b62021-11-18T08:03:45ZPERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION1563-06252313-741X10.15789/1563-0625-2015-5-461-466https://doaj.org/article/34487c0c76a84b008c8578c6e7b0a5b62015-10-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/934https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe article presents results of studies concerning subрopulations of peripheral blood lymphocyte in the patients at early stages of age-related macular degeneration (AMD), being compared with healthy elderly persons (risk group for AMD), and young adults without ophthalmological problems. We have revealed an increase in absolute counts and percentages of the cytotoxic cells (СD3+СD8+), and double-positive T cell subpopulations (СD3+CD4+СD8+), like as of B-lymphocyte contents, higher frequency of their increased content in peripheral blood of the patients with early and intermediate stages of AMD and healthy older people, as compared with young controls, thus allowing to suggest a potential role of these shifts in lymphocyte subpopulations for the AMD pathogenesis.N. V. BalatskayaE. A. EremeevaO. S. SlepovaM. V. RyabinaI. G. KulikovaE. S. SorozhkinaSPb RAACIarticlelymphocytessubpopulation profilebloodmacular degenerationage-relatedImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 17, Iss 5, Pp 461-466 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	lymphocytes subpopulation profile blood macular degeneration age-related Immunologic diseases. Allergy RC581-607
spellingShingle	lymphocytes subpopulation profile blood macular degeneration age-related Immunologic diseases. Allergy RC581-607 N. V. Balatskaya E. A. Eremeeva O. S. Slepova M. V. Ryabina I. G. Kulikova E. S. Sorozhkina PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION
description	The article presents results of studies concerning subрopulations of peripheral blood lymphocyte in the patients at early stages of age-related macular degeneration (AMD), being compared with healthy elderly persons (risk group for AMD), and young adults without ophthalmological problems. We have revealed an increase in absolute counts and percentages of the cytotoxic cells (СD3+СD8+), and double-positive T cell subpopulations (СD3+CD4+СD8+), like as of B-lymphocyte contents, higher frequency of their increased content in peripheral blood of the patients with early and intermediate stages of AMD and healthy older people, as compared with young controls, thus allowing to suggest a potential role of these shifts in lymphocyte subpopulations for the AMD pathogenesis.
format	article
author	N. V. Balatskaya E. A. Eremeeva O. S. Slepova M. V. Ryabina I. G. Kulikova E. S. Sorozhkina
author_facet	N. V. Balatskaya E. A. Eremeeva O. S. Slepova M. V. Ryabina I. G. Kulikova E. S. Sorozhkina
author_sort	N. V. Balatskaya
title	PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION
title_short	PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION
title_full	PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION
title_fullStr	PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION
title_full_unstemmed	PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION
title_sort	peripheral blood subpopulation of lymphocytes of patients with age-related macular degeneration
publisher	SPb RAACI
publishDate	2015
url	https://doaj.org/article/34487c0c76a84b008c8578c6e7b0a5b6
work_keys_str_mv	AT nvbalatskaya peripheralbloodsubpopulationoflymphocytesofpatientswithagerelatedmaculardegeneration AT eaeremeeva peripheralbloodsubpopulationoflymphocytesofpatientswithagerelatedmaculardegeneration AT osslepova peripheralbloodsubpopulationoflymphocytesofpatientswithagerelatedmaculardegeneration AT mvryabina peripheralbloodsubpopulationoflymphocytesofpatientswithagerelatedmaculardegeneration AT igkulikova peripheralbloodsubpopulationoflymphocytesofpatientswithagerelatedmaculardegeneration AT essorozhkina peripheralbloodsubpopulationoflymphocytesofpatientswithagerelatedmaculardegeneration
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PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION

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