Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae

Synthesis and turnover of the bacterial cell wall must be tightly coordinated to avoid structural integrity failure and cell death. Details of this coordination are poorly understood, particularly if and how cell wall turnover enzymes are required for the activity of the different cell wall synthes...

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Autores principales: Shannon G. Murphy, Andrew N. Murtha, Ziyi Zhao, Laura Alvarez, Peter Diebold, Jung-Ho Shin, Michael S. VanNieuwenhze, Felipe Cava, Tobias Dörr
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/3448cb1d79ee482086f35f91076bef55
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spelling oai:doaj.org-article:3448cb1d79ee482086f35f91076bef552021-11-03T18:56:10ZClass A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae2150-751110.1128/mBio.03596-20https://doaj.org/article/3448cb1d79ee482086f35f91076bef552021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03596-20https://doaj.org/toc/2150-7511 Synthesis and turnover of the bacterial cell wall must be tightly coordinated to avoid structural integrity failure and cell death. Details of this coordination are poorly understood, particularly if and how cell wall turnover enzymes are required for the activity of the different cell wall synthesis machines, the aPBPs and the Rod system.Shannon G. MurphyAndrew N. MurthaZiyi ZhaoLaura AlvarezPeter DieboldJung-Ho ShinMichael S. VanNieuwenhzeFelipe CavaTobias DörrAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Shannon G. Murphy
Andrew N. Murtha
Ziyi Zhao
Laura Alvarez
Peter Diebold
Jung-Ho Shin
Michael S. VanNieuwenhze
Felipe Cava
Tobias Dörr
Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
description Synthesis and turnover of the bacterial cell wall must be tightly coordinated to avoid structural integrity failure and cell death. Details of this coordination are poorly understood, particularly if and how cell wall turnover enzymes are required for the activity of the different cell wall synthesis machines, the aPBPs and the Rod system.
format article
author Shannon G. Murphy
Andrew N. Murtha
Ziyi Zhao
Laura Alvarez
Peter Diebold
Jung-Ho Shin
Michael S. VanNieuwenhze
Felipe Cava
Tobias Dörr
author_facet Shannon G. Murphy
Andrew N. Murtha
Ziyi Zhao
Laura Alvarez
Peter Diebold
Jung-Ho Shin
Michael S. VanNieuwenhze
Felipe Cava
Tobias Dörr
author_sort Shannon G. Murphy
title Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
title_short Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
title_full Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
title_fullStr Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
title_full_unstemmed Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
title_sort class a penicillin-binding protein-mediated cell wall synthesis promotes structural integrity during peptidoglycan endopeptidase insufficiency in vibrio cholerae
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/3448cb1d79ee482086f35f91076bef55
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