Preserving fertility in young patients with lymphoma: an overview

Bansari Patel, Brooke V Rossi Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, OH, USA Abstract: Fertility preservation affords patients the ability to reproduce after the initial diagnosis and management o...

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Autores principales:	Patel B, Rossi BV
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/344c928c913a46c1af5f831e0f0fdde6
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spelling	oai:doaj.org-article:344c928c913a46c1af5f831e0f0fdde62021-12-02T06:07:51ZPreserving fertility in young patients with lymphoma: an overview1179-9889https://doaj.org/article/344c928c913a46c1af5f831e0f0fdde62014-12-01T00:00:00Zhttp://www.dovepress.com/preserving-fertility-in-young-patients-with-lymphoma-an-overview-peer-reviewed-article-BLCTThttps://doaj.org/toc/1179-9889 Bansari Patel, Brooke V Rossi Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, OH, USA Abstract: Fertility preservation affords patients the ability to reproduce after the initial diagnosis and management of such malignancies as Hodgkin's and non-Hodgkin's lymphoma. Certain chemotherapy regimens and pelvic radiotherapy confer a high-risk of subsequent gonadal compromise in both males and females. Fortunately, early counseling and initiation of fertility-preservation strategies promptly after diagnosis enable patients to maintain hope for future reproduction. Well-established methods for fertility preservation include embryo and oocyte cryopreservation in females and sperm cryopreservation in males. These methods enable patients to utilize assisted reproductive technologies, including in vitro fertilization, at the time of desired childbearing in order to ensure genetic offspring. As most of these modalities are not feasible in some patient populations, including prepubescent patients, newer methods of fertility preservation must be created to ensure the ability to produce genetic offspring in lymphoma patients. This review provides insights into the impact of gonadotoxic treatment on ovarian and testicular function, and highlights current modalities in fertility preservation in both males and females. Keywords: fertility preservation, lymphoma, ART, egg freezingPatel BRossi BVDove Medical PressarticleDiseases of the blood and blood-forming organsRC633-647.5ENBlood and Lymphatic Cancer: Targets and Therapy, Vol 2015, Iss default, Pp 1-15 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Patel B Rossi BV Preserving fertility in young patients with lymphoma: an overview
description	Bansari Patel, Brooke V Rossi Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, OH, USA Abstract: Fertility preservation affords patients the ability to reproduce after the initial diagnosis and management of such malignancies as Hodgkin's and non-Hodgkin's lymphoma. Certain chemotherapy regimens and pelvic radiotherapy confer a high-risk of subsequent gonadal compromise in both males and females. Fortunately, early counseling and initiation of fertility-preservation strategies promptly after diagnosis enable patients to maintain hope for future reproduction. Well-established methods for fertility preservation include embryo and oocyte cryopreservation in females and sperm cryopreservation in males. These methods enable patients to utilize assisted reproductive technologies, including in vitro fertilization, at the time of desired childbearing in order to ensure genetic offspring. As most of these modalities are not feasible in some patient populations, including prepubescent patients, newer methods of fertility preservation must be created to ensure the ability to produce genetic offspring in lymphoma patients. This review provides insights into the impact of gonadotoxic treatment on ovarian and testicular function, and highlights current modalities in fertility preservation in both males and females. Keywords: fertility preservation, lymphoma, ART, egg freezing
format	article
author	Patel B Rossi BV
author_facet	Patel B Rossi BV
author_sort	Patel B
title	Preserving fertility in young patients with lymphoma: an overview
title_short	Preserving fertility in young patients with lymphoma: an overview
title_full	Preserving fertility in young patients with lymphoma: an overview
title_fullStr	Preserving fertility in young patients with lymphoma: an overview
title_full_unstemmed	Preserving fertility in young patients with lymphoma: an overview
title_sort	preserving fertility in young patients with lymphoma: an overview
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/344c928c913a46c1af5f831e0f0fdde6
work_keys_str_mv	AT patelb preservingfertilityinyoungpatientswithlymphomaanoverview AT rossibv preservingfertilityinyoungpatientswithlymphomaanoverview
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Preserving fertility in young patients with lymphoma: an overview

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