Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A

Nanopores have been used for direct observation of RNA structure in native environments but have limited RNA differentiation capabilities. Here, the authors report on the use of Mycobacterium smegmatis porin A nanopores for the trapping and translocation identification of microRNA, siRNA, tRNA and r...

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Autores principales:	Yuqin Wang, Xiaoyu Guan, Shanyu Zhang, Yao Liu, Sha Wang, Pingping Fan, Xiaoyu Du, Shuanghong Yan, Panke Zhang, Hong-Yuan Chen, Wenfei Li, Daoqiang Zhang, Shuo Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/345253368a684ae498349fa2adfed263
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spelling	oai:doaj.org-article:345253368a684ae498349fa2adfed2632021-12-02T17:52:24ZStructural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A10.1038/s41467-021-23764-y2041-1723https://doaj.org/article/345253368a684ae498349fa2adfed2632021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23764-yhttps://doaj.org/toc/2041-1723Nanopores have been used for direct observation of RNA structure in native environments but have limited RNA differentiation capabilities. Here, the authors report on the use of Mycobacterium smegmatis porin A nanopores for the trapping and translocation identification of microRNA, siRNA, tRNA and ribosomal RNA.Yuqin WangXiaoyu GuanShanyu ZhangYao LiuSha WangPingping FanXiaoyu DuShuanghong YanPanke ZhangHong-Yuan ChenWenfei LiDaoqiang ZhangShuo HuangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuqin Wang Xiaoyu Guan Shanyu Zhang Yao Liu Sha Wang Pingping Fan Xiaoyu Du Shuanghong Yan Panke Zhang Hong-Yuan Chen Wenfei Li Daoqiang Zhang Shuo Huang Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A
description	Nanopores have been used for direct observation of RNA structure in native environments but have limited RNA differentiation capabilities. Here, the authors report on the use of Mycobacterium smegmatis porin A nanopores for the trapping and translocation identification of microRNA, siRNA, tRNA and ribosomal RNA.
format	article
author	Yuqin Wang Xiaoyu Guan Shanyu Zhang Yao Liu Sha Wang Pingping Fan Xiaoyu Du Shuanghong Yan Panke Zhang Hong-Yuan Chen Wenfei Li Daoqiang Zhang Shuo Huang
author_facet	Yuqin Wang Xiaoyu Guan Shanyu Zhang Yao Liu Sha Wang Pingping Fan Xiaoyu Du Shuanghong Yan Panke Zhang Hong-Yuan Chen Wenfei Li Daoqiang Zhang Shuo Huang
author_sort	Yuqin Wang
title	Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A
title_short	Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A
title_full	Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A
title_fullStr	Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A
title_full_unstemmed	Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A
title_sort	structural-profiling of low molecular weight rnas by nanopore trapping/translocation using mycobacterium smegmatis porin a
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/345253368a684ae498349fa2adfed263
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Structural-profiling of low molecular weight RNAs by nanopore trapping/translocation using Mycobacterium smegmatis porin A

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