Peptide density targets and impedes triple negative breast cancer metastasis

The C-X-C chemokine receptor type 4 (CXCR4) pathway is a key regulator of cancer metastasis. Here, the authors present a method to block CXCR4 and thereby inhibit breast cancer metastasis by developing a liposome that presents CXCR4-binding peptides in a multivalent fashion.

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Autores principales:	Daxing Liu, Peng Guo, Craig McCarthy, Biran Wang, Yu Tao, Debra Auguste
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/34668309ab9d4d19b8e724f40b74daac
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spelling	oai:doaj.org-article:34668309ab9d4d19b8e724f40b74daac2021-12-02T14:39:08ZPeptide density targets and impedes triple negative breast cancer metastasis10.1038/s41467-018-05035-52041-1723https://doaj.org/article/34668309ab9d4d19b8e724f40b74daac2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05035-5https://doaj.org/toc/2041-1723The C-X-C chemokine receptor type 4 (CXCR4) pathway is a key regulator of cancer metastasis. Here, the authors present a method to block CXCR4 and thereby inhibit breast cancer metastasis by developing a liposome that presents CXCR4-binding peptides in a multivalent fashion.Daxing LiuPeng GuoCraig McCarthyBiran WangYu TaoDebra AugusteNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daxing Liu Peng Guo Craig McCarthy Biran Wang Yu Tao Debra Auguste Peptide density targets and impedes triple negative breast cancer metastasis
description	The C-X-C chemokine receptor type 4 (CXCR4) pathway is a key regulator of cancer metastasis. Here, the authors present a method to block CXCR4 and thereby inhibit breast cancer metastasis by developing a liposome that presents CXCR4-binding peptides in a multivalent fashion.
format	article
author	Daxing Liu Peng Guo Craig McCarthy Biran Wang Yu Tao Debra Auguste
author_facet	Daxing Liu Peng Guo Craig McCarthy Biran Wang Yu Tao Debra Auguste
author_sort	Daxing Liu
title	Peptide density targets and impedes triple negative breast cancer metastasis
title_short	Peptide density targets and impedes triple negative breast cancer metastasis
title_full	Peptide density targets and impedes triple negative breast cancer metastasis
title_fullStr	Peptide density targets and impedes triple negative breast cancer metastasis
title_full_unstemmed	Peptide density targets and impedes triple negative breast cancer metastasis
title_sort	peptide density targets and impedes triple negative breast cancer metastasis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/34668309ab9d4d19b8e724f40b74daac
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Peptide density targets and impedes triple negative breast cancer metastasis

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