Peptide density targets and impedes triple negative breast cancer metastasis
The C-X-C chemokine receptor type 4 (CXCR4) pathway is a key regulator of cancer metastasis. Here, the authors present a method to block CXCR4 and thereby inhibit breast cancer metastasis by developing a liposome that presents CXCR4-binding peptides in a multivalent fashion.
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Auteurs principaux: | Daxing Liu, Peng Guo, Craig McCarthy, Biran Wang, Yu Tao, Debra Auguste |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Sujets: | |
Accès en ligne: | https://doaj.org/article/34668309ab9d4d19b8e724f40b74daac |
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