Computational design of small transcription activating RNAs for versatile and dynamic gene regulation

The structural basis of RNA-based gene control offers the possibility of de novo design. Here the authors present a computational design approach for Small Transcription Activating RNAs a bacterial RNA regulator that allows for versatile and dynamic control of genes, pathways and genetic circuits.

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Detalles Bibliográficos
Autores principales:	James Chappell, Alexandra Westbrook, Matthew Verosloff, Julius B. Lucks
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/34680869923947a0a7d42cef28ef679d
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spelling	oai:doaj.org-article:34680869923947a0a7d42cef28ef679d2021-12-02T17:06:10ZComputational design of small transcription activating RNAs for versatile and dynamic gene regulation10.1038/s41467-017-01082-62041-1723https://doaj.org/article/34680869923947a0a7d42cef28ef679d2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01082-6https://doaj.org/toc/2041-1723The structural basis of RNA-based gene control offers the possibility of de novo design. Here the authors present a computational design approach for Small Transcription Activating RNAs a bacterial RNA regulator that allows for versatile and dynamic control of genes, pathways and genetic circuits.James ChappellAlexandra WestbrookMatthew VerosloffJulius B. LucksNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James Chappell Alexandra Westbrook Matthew Verosloff Julius B. Lucks Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
description	The structural basis of RNA-based gene control offers the possibility of de novo design. Here the authors present a computational design approach for Small Transcription Activating RNAs a bacterial RNA regulator that allows for versatile and dynamic control of genes, pathways and genetic circuits.
format	article
author	James Chappell Alexandra Westbrook Matthew Verosloff Julius B. Lucks
author_facet	James Chappell Alexandra Westbrook Matthew Verosloff Julius B. Lucks
author_sort	James Chappell
title	Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
title_short	Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
title_full	Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
title_fullStr	Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
title_full_unstemmed	Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
title_sort	computational design of small transcription activating rnas for versatile and dynamic gene regulation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/34680869923947a0a7d42cef28ef679d
work_keys_str_mv	AT jameschappell computationaldesignofsmalltranscriptionactivatingrnasforversatileanddynamicgeneregulation AT alexandrawestbrook computationaldesignofsmalltranscriptionactivatingrnasforversatileanddynamicgeneregulation AT matthewverosloff computationaldesignofsmalltranscriptionactivatingrnasforversatileanddynamicgeneregulation AT juliusblucks computationaldesignofsmalltranscriptionactivatingrnasforversatileanddynamicgeneregulation
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Computational design of small transcription activating RNAs for versatile and dynamic gene regulation

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