Cisplatin induced neurotoxicity is mediated by Sarm1 and calpain activation
Abstract Cisplatin is a commonly used chemotherapy agent with significant dose-limiting neurotoxicity resulting in peripheral neuropathy. Although it is postulated that formation of DNA-platinum adducts is responsible for both its cytotoxicity in cancer cells and side effects in neurons, downstream...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/34702de21add40cd9739b7d7b3070316 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|