Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

Epithelial cells that line the gut secrete complex glycoproteins that form a mucus layer to protect the gut wall from enteric pathogens. Here, the authors provide a comprehensive characterisation of endo-acting glycoside hydrolases expressed by mucin-degrading members of the microbiome that are able...

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Bibliographic Details
Main Authors: Lucy I. Crouch, Marcelo V. Liberato, Paulina A. Urbanowicz, Arnaud Baslé, Christopher A. Lamb, Christopher J. Stewart, Katie Cooke, Mary Doona, Stephanie Needham, Richard R. Brady, Janet E. Berrington, Katarina Madunic, Manfred Wuhrer, Peter Chater, Jeffery P. Pearson, Robert Glowacki, Eric C. Martens, Fuming Zhang, Robert J. Linhardt, Daniel I. R. Spencer, David N. Bolam
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/34729e0035e248979eeaf2cddb4c661b
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