2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions

2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions

UV-induced photodamage that likely occurred during the prebiotic synthesis of DNA and RNA is still an untackled issue for their origin on early Earth. Here, the authors show that substitution of 2,6-diaminopurine for adenine enables repair of cyclobutane pyrimidine dimers with high yields, and demon...

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Autores principales: Rafał Szabla, Magdalena Zdrowowicz, Paulina Spisz, Nicholas J. Green, Petr Stadlbauer, Holger Kruse, Jiří Šponer, Janusz Rak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/347696f7b33c4b0fa6bc7bc725ea0853
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