Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulation
Uncoupling of mature oocytes from somatic granulosa cells is required for their fertilization. Here the authors show that activation of EGFR signalling in granulosa cells during ovulation triggers ERK-dependent loss of filopodia oocyte adhesion, and Arp2/3 mediated retraction of granulosa cell filop...
Guardado en:
Autores principales: | Laleh Abbassi, Stephany El-Hayek, Karen Freire Carvalho, Wusu Wang, Qin Yang, Sofia Granados-Aparici, Rafael Mondadori, Vilceu Bordignon, Hugh J. Clarke |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/348d0733017a4b4c8fcd9963a3acfe35 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transcriptomic signature of the follicular somatic compartment surrounding an oocyte with high developmental competence
por: Satoshi Sugimura, et al.
Publicado: (2017) -
A somatic proteoglycan controls Notch-directed germ cell fate
por: Sandeep Gopal, et al.
Publicado: (2021) -
Delayed Ovulation in Bovine: Diagnosis and Treatment
por: Al-Timimi I. H., et al.
Publicado: (2021) -
Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia
por: Massimo Alfano, et al.
Publicado: (2021) -
Recent advancements in the hormonal stimulation of ovulation in swine
por: Knox RV
Publicado: (2015)