TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with the core transcription-coupled nucleotide excision...

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Autores principales: Alex Pines, Madelon Dijk, Matthew Makowski, Elisabeth M. Meulenbroek, Mischa G. Vrouwe, Yana van der Weegen, Marijke Baltissen, Pim J. French, Martin E. van Royen, Martijn S. Luijsterburg, Leon H. Mullenders, Michiel Vermeulen, Wim Vermeulen, Navraj S. Pannu, Haico van Attikum
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/349d895dc8574c5db3919c1594d1d33a
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spelling oai:doaj.org-article:349d895dc8574c5db3919c1594d1d33a2021-12-02T16:56:35ZTRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A10.1038/s41467-018-03484-62041-1723https://doaj.org/article/349d895dc8574c5db3919c1594d1d33a2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03484-6https://doaj.org/toc/2041-1723An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with the core transcription-coupled nucleotide excision repair protein CSA to ensure its assembly into the CRLCSA complex.Alex PinesMadelon DijkMatthew MakowskiElisabeth M. MeulenbroekMischa G. VrouweYana van der WeegenMarijke BaltissenPim J. FrenchMartin E. van RoyenMartijn S. LuijsterburgLeon H. MullendersMichiel VermeulenWim VermeulenNavraj S. PannuHaico van AttikumNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alex Pines
Madelon Dijk
Matthew Makowski
Elisabeth M. Meulenbroek
Mischa G. Vrouwe
Yana van der Weegen
Marijke Baltissen
Pim J. French
Martin E. van Royen
Martijn S. Luijsterburg
Leon H. Mullenders
Michiel Vermeulen
Wim Vermeulen
Navraj S. Pannu
Haico van Attikum
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
description An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with the core transcription-coupled nucleotide excision repair protein CSA to ensure its assembly into the CRLCSA complex.
format article
author Alex Pines
Madelon Dijk
Matthew Makowski
Elisabeth M. Meulenbroek
Mischa G. Vrouwe
Yana van der Weegen
Marijke Baltissen
Pim J. French
Martin E. van Royen
Martijn S. Luijsterburg
Leon H. Mullenders
Michiel Vermeulen
Wim Vermeulen
Navraj S. Pannu
Haico van Attikum
author_facet Alex Pines
Madelon Dijk
Matthew Makowski
Elisabeth M. Meulenbroek
Mischa G. Vrouwe
Yana van der Weegen
Marijke Baltissen
Pim J. French
Martin E. van Royen
Martijn S. Luijsterburg
Leon H. Mullenders
Michiel Vermeulen
Wim Vermeulen
Navraj S. Pannu
Haico van Attikum
author_sort Alex Pines
title TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
title_short TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
title_full TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
title_fullStr TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
title_full_unstemmed TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
title_sort tric controls transcription resumption after uv damage by regulating cockayne syndrome protein a
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/349d895dc8574c5db3919c1594d1d33a
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