TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with the core transcription-coupled nucleotide excision...
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Nature Portfolio
2018
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oai:doaj.org-article:349d895dc8574c5db3919c1594d1d33a2021-12-02T16:56:35ZTRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A10.1038/s41467-018-03484-62041-1723https://doaj.org/article/349d895dc8574c5db3919c1594d1d33a2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03484-6https://doaj.org/toc/2041-1723An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with the core transcription-coupled nucleotide excision repair protein CSA to ensure its assembly into the CRLCSA complex.Alex PinesMadelon DijkMatthew MakowskiElisabeth M. MeulenbroekMischa G. VrouweYana van der WeegenMarijke BaltissenPim J. FrenchMartin E. van RoyenMartijn S. LuijsterburgLeon H. MullendersMichiel VermeulenWim VermeulenNavraj S. PannuHaico van AttikumNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Alex Pines Madelon Dijk Matthew Makowski Elisabeth M. Meulenbroek Mischa G. Vrouwe Yana van der Weegen Marijke Baltissen Pim J. French Martin E. van Royen Martijn S. Luijsterburg Leon H. Mullenders Michiel Vermeulen Wim Vermeulen Navraj S. Pannu Haico van Attikum TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A |
description |
An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with the core transcription-coupled nucleotide excision repair protein CSA to ensure its assembly into the CRLCSA complex. |
format |
article |
author |
Alex Pines Madelon Dijk Matthew Makowski Elisabeth M. Meulenbroek Mischa G. Vrouwe Yana van der Weegen Marijke Baltissen Pim J. French Martin E. van Royen Martijn S. Luijsterburg Leon H. Mullenders Michiel Vermeulen Wim Vermeulen Navraj S. Pannu Haico van Attikum |
author_facet |
Alex Pines Madelon Dijk Matthew Makowski Elisabeth M. Meulenbroek Mischa G. Vrouwe Yana van der Weegen Marijke Baltissen Pim J. French Martin E. van Royen Martijn S. Luijsterburg Leon H. Mullenders Michiel Vermeulen Wim Vermeulen Navraj S. Pannu Haico van Attikum |
author_sort |
Alex Pines |
title |
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A |
title_short |
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A |
title_full |
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A |
title_fullStr |
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A |
title_full_unstemmed |
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A |
title_sort |
tric controls transcription resumption after uv damage by regulating cockayne syndrome protein a |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/349d895dc8574c5db3919c1594d1d33a |
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