Factors of tubulointerstitial lesions in diabetic kidneys

As the number of cases with classical manifestations of diabetic nephropathy (DN), i.e. nodular or diffuse glomerulosclerosis, grows, an increasinglylarger number of DM patients especially those with DM2 present with renal pathology largely affecting interstitium and tubules (ischemic nephropathy,ur...

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Autores principales:	Minara Shamkhalovna Shamkhalova, Kseniya Olegovna Kurumova, Marina Vladimirovna Shestakova
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2009
Materias:	diabetes mellitus tubulointerstitial fibrosis chronic renal failure Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/34a3a360cc774915875b5402765dcbe3
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spelling	oai:doaj.org-article:34a3a360cc774915875b5402765dcbe32021-11-14T09:00:14ZFactors of tubulointerstitial lesions in diabetic kidneys2072-03512072-037810.14341/2072-0351-5707https://doaj.org/article/34a3a360cc774915875b5402765dcbe32009-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5707https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378As the number of cases with classical manifestations of diabetic nephropathy (DN), i.e. nodular or diffuse glomerulosclerosis, grows, an increasinglylarger number of DM patients especially those with DM2 present with renal pathology largely affecting interstitium and tubules (ischemic nephropathy,urinary infection, interstitial nephritis, etc.). The rate of renal filtration impairment in glomerular diseases (DN, glomerulonephritis) is also relatedto the severity of tubulointerstitial fibrosis (TIF). Intricate intercellular interactions activated by immune and non-immune factors have been shownto play an important role in the development of tubulointerstitial lesions. Studies of the most important factors contributing to remodeling tubulointerstitiumin DM patients may provide a deeper insight into the mechanisms of nephrosclerosis and extend possibilities for prognostication of renalfunction.Minara Shamkhalovna ShamkhalovaKseniya Olegovna KurumovaMarina Vladimirovna ShestakovaEndocrinology Research Centrearticlediabetes mellitustubulointerstitial fibrosischronic renal failureNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 12, Iss 4, Pp 61-65 (2009)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus tubulointerstitial fibrosis chronic renal failure Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus tubulointerstitial fibrosis chronic renal failure Nutritional diseases. Deficiency diseases RC620-627 Minara Shamkhalovna Shamkhalova Kseniya Olegovna Kurumova Marina Vladimirovna Shestakova Factors of tubulointerstitial lesions in diabetic kidneys
description	As the number of cases with classical manifestations of diabetic nephropathy (DN), i.e. nodular or diffuse glomerulosclerosis, grows, an increasinglylarger number of DM patients especially those with DM2 present with renal pathology largely affecting interstitium and tubules (ischemic nephropathy,urinary infection, interstitial nephritis, etc.). The rate of renal filtration impairment in glomerular diseases (DN, glomerulonephritis) is also relatedto the severity of tubulointerstitial fibrosis (TIF). Intricate intercellular interactions activated by immune and non-immune factors have been shownto play an important role in the development of tubulointerstitial lesions. Studies of the most important factors contributing to remodeling tubulointerstitiumin DM patients may provide a deeper insight into the mechanisms of nephrosclerosis and extend possibilities for prognostication of renalfunction.
format	article
author	Minara Shamkhalovna Shamkhalova Kseniya Olegovna Kurumova Marina Vladimirovna Shestakova
author_facet	Minara Shamkhalovna Shamkhalova Kseniya Olegovna Kurumova Marina Vladimirovna Shestakova
author_sort	Minara Shamkhalovna Shamkhalova
title	Factors of tubulointerstitial lesions in diabetic kidneys
title_short	Factors of tubulointerstitial lesions in diabetic kidneys
title_full	Factors of tubulointerstitial lesions in diabetic kidneys
title_fullStr	Factors of tubulointerstitial lesions in diabetic kidneys
title_full_unstemmed	Factors of tubulointerstitial lesions in diabetic kidneys
title_sort	factors of tubulointerstitial lesions in diabetic kidneys
publisher	Endocrinology Research Centre
publishDate	2009
url	https://doaj.org/article/34a3a360cc774915875b5402765dcbe3
work_keys_str_mv	AT minarashamkhalovnashamkhalova factorsoftubulointerstitiallesionsindiabetickidneys AT kseniyaolegovnakurumova factorsoftubulointerstitiallesionsindiabetickidneys AT marinavladimirovnashestakova factorsoftubulointerstitiallesionsindiabetickidneys
_version_	1718429640556544000

Factors of tubulointerstitial lesions in diabetic kidneys

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