R-spondins are BMP receptor antagonists in Xenopus early embryonic development

R-spondins are BMP receptor antagonists in Xenopus early embryonic development

R-spondins are known modulators of Wnt signaling. Here, the authors demonstrate that R-spondins function in Xenopus embryonic development as BMP antagonists by targeting BMP receptor 1A for degradation.

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Autores principales: Hyeyoon Lee, Carina Seidl, Rui Sun, Andrey Glinka, Christof Niehrs
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/34a5e992ac2c477285dd80f3a3141eee
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