Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure

There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation on exposure to cigarette smoke abstract.

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Autores principales: Vlasta Lungova, Xia Chen, Ziyue Wang, Christina Kendziorski, Susan L. Thibeault
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/34aff485983d44beb8daab94f4462674
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Sumario:There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation on exposure to cigarette smoke abstract.