Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation on exposure to cigarette smoke abstract.
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Nature Portfolio
2019
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oai:doaj.org-article:34aff485983d44beb8daab94f44626742021-12-02T17:31:22ZHuman induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure10.1038/s41467-019-12069-w2041-1723https://doaj.org/article/34aff485983d44beb8daab94f44626742019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12069-whttps://doaj.org/toc/2041-1723There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation on exposure to cigarette smoke abstract.Vlasta LungovaXia ChenZiyue WangChristina KendziorskiSusan L. ThibeaultNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Vlasta Lungova Xia Chen Ziyue Wang Christina Kendziorski Susan L. Thibeault Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
description |
There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation on exposure to cigarette smoke abstract. |
format |
article |
author |
Vlasta Lungova Xia Chen Ziyue Wang Christina Kendziorski Susan L. Thibeault |
author_facet |
Vlasta Lungova Xia Chen Ziyue Wang Christina Kendziorski Susan L. Thibeault |
author_sort |
Vlasta Lungova |
title |
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
title_short |
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
title_full |
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
title_fullStr |
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
title_full_unstemmed |
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
title_sort |
human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/34aff485983d44beb8daab94f4462674 |
work_keys_str_mv |
AT vlastalungova humaninducedpluripotentstemcellderivedvocalfoldmucosamimicsdevelopmentandresponsestosmokeexposure AT xiachen humaninducedpluripotentstemcellderivedvocalfoldmucosamimicsdevelopmentandresponsestosmokeexposure AT ziyuewang humaninducedpluripotentstemcellderivedvocalfoldmucosamimicsdevelopmentandresponsestosmokeexposure AT christinakendziorski humaninducedpluripotentstemcellderivedvocalfoldmucosamimicsdevelopmentandresponsestosmokeexposure AT susanlthibeault humaninducedpluripotentstemcellderivedvocalfoldmucosamimicsdevelopmentandresponsestosmokeexposure |
_version_ |
1718380604542681088 |