Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles
Host kinases facilitate Plasmodium liver stage (LS) infection, but systematic accounting of important players is lacking. Here, the authors use a computational approach and kinase activity profiles to identify host kinase regulators of LS infection and drugs that could eliminate parasite burden.
Guardado en:
Autores principales: | Nadia Arang, Heather S. Kain, Elizabeth K. Glennon, Thomas Bello, Denali R. Dudgeon, Emily N. F. Walter, Taranjit S. Gujral, Alexis Kaushansky |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/34b30dc350304d7da86e97eaeab203a7 |
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