Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

Host kinases facilitate Plasmodium liver stage (LS) infection, but systematic accounting of important players is lacking. Here, the authors use a computational approach and kinase activity profiles to identify host kinase regulators of LS infection and drugs that could eliminate parasite burden.

Saved in:
Bibliographic Details
Main Authors: Nadia Arang, Heather S. Kain, Elizabeth K. Glennon, Thomas Bello, Denali R. Dudgeon, Emily N. F. Walter, Taranjit S. Gujral, Alexis Kaushansky
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/34b30dc350304d7da86e97eaeab203a7
Tags: Add Tag
No Tags, Be the first to tag this record!