A stochastic view on surface inhomogeneity of nanoparticles

Determining the spatial arrangement of molecules on a nanoparticle’s surface is key to understanding its interactions. Here, the authors use dSTORM imaging and probabilistic modelling to map the distribution of fluorophores on a nanoparticle, finding that ligand coverage is heterogeneous and highly...

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Autores principales: R. A. J. Post, D. van der Zwaag, G. Bet, S. P. W. Wijnands, L. Albertazzi, E. W. Meijer, R. W. van der Hofstad
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/34cb2e14387845d899b68a5d07e07b57
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Sumario:Determining the spatial arrangement of molecules on a nanoparticle’s surface is key to understanding its interactions. Here, the authors use dSTORM imaging and probabilistic modelling to map the distribution of fluorophores on a nanoparticle, finding that ligand coverage is heterogeneous and highly variable between individual particles.