Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes

Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes

Osteoarthritis (OA) is recognized as being a cellular senescence-linked disease. Intra-articular injections of glucocorticoids (GC) are frequently used in knee OA to treat synovial effusion but face controversies about toxicity. We investigated the influence of GC on cellular senescence hallmarks an...

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Autores principales: Olivier Malaise, Geneviève Paulissen, Céline Deroyer, Federica Ciregia, Christophe Poulet, Sophie Neuville, Zelda Plener, Christophe Daniel, Philippe Gillet, Chantal Lechanteur, Jean-Marc Brondello, Dominique de Seny, Michel Malaise
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
osteoarthritis
synovial membrane
clinical studies
Medicine
R
Acceso en línea:https://doaj.org/article/34cc2a99573a4e5a867fd07d7f611b83
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