Next-Generation Sequencing of Small RNAs from HIV-Infected Cells Identifies Phased microRNA Expression Patterns and Candidate Novel microRNAs Differentially Expressed upon Infection

ABSTRACT HIV infection of CD4+ T cells induces a range of host transcriptional changes in mRNAs as well as microRNAs that may coordinate changes in mRNAs. To survey these dynamic changes, we applied next-generation sequencing, analyzing the small RNA fraction of HIV-infected cells at 5, 12, and 24 h...

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Autores principales: Stewart T. Chang, Matthew J. Thomas, Pavel Sova, Richard R. Green, Robert E. Palermo, Michael G. Katze
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://doaj.org/article/34dcfe49b7474662bc2f271122daeb5d
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