Next-Generation Sequencing of Small RNAs from HIV-Infected Cells Identifies Phased microRNA Expression Patterns and Candidate Novel microRNAs Differentially Expressed upon Infection
ABSTRACT HIV infection of CD4+ T cells induces a range of host transcriptional changes in mRNAs as well as microRNAs that may coordinate changes in mRNAs. To survey these dynamic changes, we applied next-generation sequencing, analyzing the small RNA fraction of HIV-infected cells at 5, 12, and 24 h...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2013
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Subjects: | |
Online Access: | https://doaj.org/article/34dcfe49b7474662bc2f271122daeb5d |
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