Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

The Patch-seq approach is a powerful variation of the patch-clamp technique that allows for the combined electrophysiological, morphological, and transcriptomic characterization of individual neurons. To generate Patch-seq datasets at scale, we identified and refined key factors that contribute to t...

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Bibliographic Details
Main Authors: Brian R Lee, Agata Budzillo, Kristen Hadley, Jeremy A Miller, Tim Jarsky, Katherine Baker, DiJon Hill, Lisa Kim, Rusty Mann, Lindsay Ng, Aaron Oldre, Ram Rajanbabu, Jessica Trinh, Sara Vargas, Thomas Braun, Rachel A Dalley, Nathan W Gouwens, Brian E Kalmbach, Tae Kyung Kim, Kimberly A Smith, Gilberto Soler-Llavina, Staci Sorensen, Bosiljka Tasic, Jonathan T Ting, Ed Lein, Hongkui Zeng, Gabe J Murphy, Jim Berg
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
patch-seq
electrophysiology
morphology
transcriptomics
RNA-seq
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/34e4a68dbc504e52805f073d4e7d3060
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