Effect of HIV infection on time to recovery from an acute manic episode

E Nakimuli-Mpungu1,2,3, B Mutamba2,3, S Nshemerirwe2,3, MS Kiwuwa4, S Musisi21Mental Health Department, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; 2Department of Psychiatry, Makerere College of Health Sciences, School of Medicine, Kampala; 3Butabika National Referral...

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Autores principales:	E Nakimuli-Mpungu, B Mutamba, S Nshemerirwe, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/34ed94b29198468ab687098428da48a6
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spelling	oai:doaj.org-article:34ed94b29198468ab687098428da48a62021-12-02T02:08:06ZEffect of HIV infection on time to recovery from an acute manic episode1179-1373https://doaj.org/article/34ed94b29198468ab687098428da48a62010-09-01T00:00:00Zhttp://www.dovepress.com/effect-of-hiv-infection-on-time-to-recovery-from-an-acute-manic-episod-a5394https://doaj.org/toc/1179-1373E Nakimuli-Mpungu1,2,3, B Mutamba2,3, S Nshemerirwe2,3, MS Kiwuwa4, S Musisi21Mental Health Department, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; 2Department of Psychiatry, Makerere College of Health Sciences, School of Medicine, Kampala; 3Butabika National Referral Mental Hospital, Ministry of Health, Kampala; 4Clinical Epidemiology Unit, Makerere College of Health Sciences, School of Medicine, Kampala, UgandaIntroduction: Understanding factors affecting the time to recovery from acute mania is critical in the management of manic syndromes. The aim of this study was to determine the effect of HIV infection on time to recovery from acute mania.Methods: We performed a retrospective study in which medical charts of individuals who were treated for acute mania were reviewed. Survival analysis with Cox regression models were used to compare time to recovery from an acute manic episode between human immunodeficiency virus (HIV)-positive individuals and HIV-negative individuals.Results: Median survival time was one week for HIV-positive individuals and more than four weeks for HIV-negative individuals (&Chi;2 = 18.4, P value = 0.000). HIV infection was the only marginally significant independent predictor of survival probability on the acute admission ward (hazards ratio 2.87, P = 0.06).Conclusion: Acute mania in HIV-infected persons responds faster to psychotropic drugs compared with that in HIV-negative persons.Keywords: HIV-related mania, bipolar disorder, HIV infection, Uganda, immunodeficiency virus E Nakimuli-MpunguB MutambaS Nshemerirweet alDove Medical PressarticleImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol 2010, Iss default, Pp 185-189 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607
spellingShingle	Immunologic diseases. Allergy RC581-607 E Nakimuli-Mpungu B Mutamba S Nshemerirwe et al Effect of HIV infection on time to recovery from an acute manic episode
description	E Nakimuli-Mpungu1,2,3, B Mutamba2,3, S Nshemerirwe2,3, MS Kiwuwa4, S Musisi21Mental Health Department, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; 2Department of Psychiatry, Makerere College of Health Sciences, School of Medicine, Kampala; 3Butabika National Referral Mental Hospital, Ministry of Health, Kampala; 4Clinical Epidemiology Unit, Makerere College of Health Sciences, School of Medicine, Kampala, UgandaIntroduction: Understanding factors affecting the time to recovery from acute mania is critical in the management of manic syndromes. The aim of this study was to determine the effect of HIV infection on time to recovery from acute mania.Methods: We performed a retrospective study in which medical charts of individuals who were treated for acute mania were reviewed. Survival analysis with Cox regression models were used to compare time to recovery from an acute manic episode between human immunodeficiency virus (HIV)-positive individuals and HIV-negative individuals.Results: Median survival time was one week for HIV-positive individuals and more than four weeks for HIV-negative individuals (&Chi;2 = 18.4, P value = 0.000). HIV infection was the only marginally significant independent predictor of survival probability on the acute admission ward (hazards ratio 2.87, P = 0.06).Conclusion: Acute mania in HIV-infected persons responds faster to psychotropic drugs compared with that in HIV-negative persons.Keywords: HIV-related mania, bipolar disorder, HIV infection, Uganda, immunodeficiency virus
format	article
author	E Nakimuli-Mpungu B Mutamba S Nshemerirwe et al
author_facet	E Nakimuli-Mpungu B Mutamba S Nshemerirwe et al
author_sort	E Nakimuli-Mpungu
title	Effect of HIV infection on time to recovery from an acute manic episode
title_short	Effect of HIV infection on time to recovery from an acute manic episode
title_full	Effect of HIV infection on time to recovery from an acute manic episode
title_fullStr	Effect of HIV infection on time to recovery from an acute manic episode
title_full_unstemmed	Effect of HIV infection on time to recovery from an acute manic episode
title_sort	effect of hiv infection on time to recovery from an acute manic episode
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/34ed94b29198468ab687098428da48a6
work_keys_str_mv	AT enakimulimpungu effectofhivinfectionontimetorecoveryfromanacutemanicepisode AT bmutamba effectofhivinfectionontimetorecoveryfromanacutemanicepisode AT snshemerirwe effectofhivinfectionontimetorecoveryfromanacutemanicepisode AT etal effectofhivinfectionontimetorecoveryfromanacutemanicepisode
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Effect of HIV infection on time to recovery from an acute manic episode

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