Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo

What breaks symmetry in early mammalian embryonic development has been much questioned. Here, Magdalena Zernicka-Goetz and colleagues propose that compartmentalized intracellular reactions generate micro-scale inhomogeneity, which is amplified in the developing embryo, driving pattern formation.

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Autores principales:	Qi Chen, Junchao Shi, Yi Tao, Magdalena Zernicka-Goetz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/34f4ad89145e450a8f654040cd5bc6eb
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spelling	oai:doaj.org-article:34f4ad89145e450a8f654040cd5bc6eb2021-12-02T16:49:22ZTracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo10.1038/s41467-018-04155-22041-1723https://doaj.org/article/34f4ad89145e450a8f654040cd5bc6eb2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04155-2https://doaj.org/toc/2041-1723What breaks symmetry in early mammalian embryonic development has been much questioned. Here, Magdalena Zernicka-Goetz and colleagues propose that compartmentalized intracellular reactions generate micro-scale inhomogeneity, which is amplified in the developing embryo, driving pattern formation.Qi ChenJunchao ShiYi TaoMagdalena Zernicka-GoetzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qi Chen Junchao Shi Yi Tao Magdalena Zernicka-Goetz Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
description	What breaks symmetry in early mammalian embryonic development has been much questioned. Here, Magdalena Zernicka-Goetz and colleagues propose that compartmentalized intracellular reactions generate micro-scale inhomogeneity, which is amplified in the developing embryo, driving pattern formation.
format	article
author	Qi Chen Junchao Shi Yi Tao Magdalena Zernicka-Goetz
author_facet	Qi Chen Junchao Shi Yi Tao Magdalena Zernicka-Goetz
author_sort	Qi Chen
title	Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
title_short	Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
title_full	Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
title_fullStr	Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
title_full_unstemmed	Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
title_sort	tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/34f4ad89145e450a8f654040cd5bc6eb
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Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo

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