Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
What breaks symmetry in early mammalian embryonic development has been much questioned. Here, Magdalena Zernicka-Goetz and colleagues propose that compartmentalized intracellular reactions generate micro-scale inhomogeneity, which is amplified in the developing embryo, driving pattern formation.
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Autores principales: | Qi Chen, Junchao Shi, Yi Tao, Magdalena Zernicka-Goetz |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/34f4ad89145e450a8f654040cd5bc6eb |
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