Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo

What breaks symmetry in early mammalian embryonic development has been much questioned. Here, Magdalena Zernicka-Goetz and colleagues propose that compartmentalized intracellular reactions generate micro-scale inhomogeneity, which is amplified in the developing embryo, driving pattern formation.

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Bibliographic Details
Main Authors: Qi Chen, Junchao Shi, Yi Tao, Magdalena Zernicka-Goetz
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/34f4ad89145e450a8f654040cd5bc6eb
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