Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes
Many bacterial proteins exhibit spatially defined localization important for function. Here the authors show that the polar localization of Shigella IpaC type III secretion substrate is mediated by its interaction with the DnaK chaperone and occlusion by the bacterial nucleoid.
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Nature Portfolio
2018
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oai:doaj.org-article:34f8c4d1222449c3af8aeff533690b222021-12-02T16:49:48ZProtein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes10.1038/s41467-018-04414-22041-1723https://doaj.org/article/34f8c4d1222449c3af8aeff533690b222018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04414-2https://doaj.org/toc/2041-1723Many bacterial proteins exhibit spatially defined localization important for function. Here the authors show that the polar localization of Shigella IpaC type III secretion substrate is mediated by its interaction with the DnaK chaperone and occlusion by the bacterial nucleoid.Clémence ColletJenny-Lee ThomassinOlivera FranceticPierre GenevauxGuy Tran Van NhieuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Clémence Collet Jenny-Lee Thomassin Olivera Francetic Pierre Genevaux Guy Tran Van Nhieu Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes |
description |
Many bacterial proteins exhibit spatially defined localization important for function. Here the authors show that the polar localization of Shigella IpaC type III secretion substrate is mediated by its interaction with the DnaK chaperone and occlusion by the bacterial nucleoid. |
format |
article |
author |
Clémence Collet Jenny-Lee Thomassin Olivera Francetic Pierre Genevaux Guy Tran Van Nhieu |
author_facet |
Clémence Collet Jenny-Lee Thomassin Olivera Francetic Pierre Genevaux Guy Tran Van Nhieu |
author_sort |
Clémence Collet |
title |
Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes |
title_short |
Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes |
title_full |
Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes |
title_fullStr |
Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes |
title_full_unstemmed |
Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes |
title_sort |
protein polarization driven by nucleoid exclusion of dnak(hsp70)–substrate complexes |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/34f8c4d1222449c3af8aeff533690b22 |
work_keys_str_mv |
AT clemencecollet proteinpolarizationdrivenbynucleoidexclusionofdnakhsp70substratecomplexes AT jennyleethomassin proteinpolarizationdrivenbynucleoidexclusionofdnakhsp70substratecomplexes AT oliverafrancetic proteinpolarizationdrivenbynucleoidexclusionofdnakhsp70substratecomplexes AT pierregenevaux proteinpolarizationdrivenbynucleoidexclusionofdnakhsp70substratecomplexes AT guytranvannhieu proteinpolarizationdrivenbynucleoidexclusionofdnakhsp70substratecomplexes |
_version_ |
1718383207681884160 |