Membrane protein-regulated networks across human cancers

Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.

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Detalles Bibliográficos
Autores principales: Chun-Yu Lin, Chia-Hwa Lee, Yi-Hsuan Chuang, Jung-Yu Lee, Yi-Yuan Chiu, Yan-Hwa Wu Lee, Yuh-Jyh Jong, Jenn-Kang Hwang, Sing-Han Huang, Li-Ching Chen, Chih-Hsiung Wu, Shih-Hsin Tu, Yuan-Soon Ho, Jinn-Moon Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a016
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Sumario:Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.