Membrane protein-regulated networks across human cancers
Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.
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Nature Portfolio
2019
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oai:doaj.org-article:34ff9a3b0c684e9db11e11f9aee3a0162021-12-02T14:39:02ZMembrane protein-regulated networks across human cancers10.1038/s41467-019-10920-82041-1723https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a0162019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10920-8https://doaj.org/toc/2041-1723Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.Chun-Yu LinChia-Hwa LeeYi-Hsuan ChuangJung-Yu LeeYi-Yuan ChiuYan-Hwa Wu LeeYuh-Jyh JongJenn-Kang HwangSing-Han HuangLi-Ching ChenChih-Hsiung WuShih-Hsin TuYuan-Soon HoJinn-Moon YangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019) |
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Science Q |
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Science Q Chun-Yu Lin Chia-Hwa Lee Yi-Hsuan Chuang Jung-Yu Lee Yi-Yuan Chiu Yan-Hwa Wu Lee Yuh-Jyh Jong Jenn-Kang Hwang Sing-Han Huang Li-Ching Chen Chih-Hsiung Wu Shih-Hsin Tu Yuan-Soon Ho Jinn-Moon Yang Membrane protein-regulated networks across human cancers |
description |
Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification. |
format |
article |
author |
Chun-Yu Lin Chia-Hwa Lee Yi-Hsuan Chuang Jung-Yu Lee Yi-Yuan Chiu Yan-Hwa Wu Lee Yuh-Jyh Jong Jenn-Kang Hwang Sing-Han Huang Li-Ching Chen Chih-Hsiung Wu Shih-Hsin Tu Yuan-Soon Ho Jinn-Moon Yang |
author_facet |
Chun-Yu Lin Chia-Hwa Lee Yi-Hsuan Chuang Jung-Yu Lee Yi-Yuan Chiu Yan-Hwa Wu Lee Yuh-Jyh Jong Jenn-Kang Hwang Sing-Han Huang Li-Ching Chen Chih-Hsiung Wu Shih-Hsin Tu Yuan-Soon Ho Jinn-Moon Yang |
author_sort |
Chun-Yu Lin |
title |
Membrane protein-regulated networks across human cancers |
title_short |
Membrane protein-regulated networks across human cancers |
title_full |
Membrane protein-regulated networks across human cancers |
title_fullStr |
Membrane protein-regulated networks across human cancers |
title_full_unstemmed |
Membrane protein-regulated networks across human cancers |
title_sort |
membrane protein-regulated networks across human cancers |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a016 |
work_keys_str_mv |
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