Membrane protein-regulated networks across human cancers

Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.

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Autores principales: Chun-Yu Lin, Chia-Hwa Lee, Yi-Hsuan Chuang, Jung-Yu Lee, Yi-Yuan Chiu, Yan-Hwa Wu Lee, Yuh-Jyh Jong, Jenn-Kang Hwang, Sing-Han Huang, Li-Ching Chen, Chih-Hsiung Wu, Shih-Hsin Tu, Yuan-Soon Ho, Jinn-Moon Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a016
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spelling oai:doaj.org-article:34ff9a3b0c684e9db11e11f9aee3a0162021-12-02T14:39:02ZMembrane protein-regulated networks across human cancers10.1038/s41467-019-10920-82041-1723https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a0162019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10920-8https://doaj.org/toc/2041-1723Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.Chun-Yu LinChia-Hwa LeeYi-Hsuan ChuangJung-Yu LeeYi-Yuan ChiuYan-Hwa Wu LeeYuh-Jyh JongJenn-Kang HwangSing-Han HuangLi-Ching ChenChih-Hsiung WuShih-Hsin TuYuan-Soon HoJinn-Moon YangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chun-Yu Lin
Chia-Hwa Lee
Yi-Hsuan Chuang
Jung-Yu Lee
Yi-Yuan Chiu
Yan-Hwa Wu Lee
Yuh-Jyh Jong
Jenn-Kang Hwang
Sing-Han Huang
Li-Ching Chen
Chih-Hsiung Wu
Shih-Hsin Tu
Yuan-Soon Ho
Jinn-Moon Yang
Membrane protein-regulated networks across human cancers
description Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker development and druggable target identification.
format article
author Chun-Yu Lin
Chia-Hwa Lee
Yi-Hsuan Chuang
Jung-Yu Lee
Yi-Yuan Chiu
Yan-Hwa Wu Lee
Yuh-Jyh Jong
Jenn-Kang Hwang
Sing-Han Huang
Li-Ching Chen
Chih-Hsiung Wu
Shih-Hsin Tu
Yuan-Soon Ho
Jinn-Moon Yang
author_facet Chun-Yu Lin
Chia-Hwa Lee
Yi-Hsuan Chuang
Jung-Yu Lee
Yi-Yuan Chiu
Yan-Hwa Wu Lee
Yuh-Jyh Jong
Jenn-Kang Hwang
Sing-Han Huang
Li-Ching Chen
Chih-Hsiung Wu
Shih-Hsin Tu
Yuan-Soon Ho
Jinn-Moon Yang
author_sort Chun-Yu Lin
title Membrane protein-regulated networks across human cancers
title_short Membrane protein-regulated networks across human cancers
title_full Membrane protein-regulated networks across human cancers
title_fullStr Membrane protein-regulated networks across human cancers
title_full_unstemmed Membrane protein-regulated networks across human cancers
title_sort membrane protein-regulated networks across human cancers
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a016
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