Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene.

Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene.

A large percentage of prostate cancers harbor TMPRSS2-ERG gene fusions, leading to aberrant overexpression of the transcription factor ERG. The target genes deregulated by this rearrangement, however, remain mostly unknown. To address this subject we performed genome-wide mRNA expression analysis on...

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Autores principales: Franclim R Ribeiro, Paula Paulo, Vera L Costa, João D Barros-Silva, João Ramalho-Carvalho, Carmen Jerónimo, Rui Henrique, Guro E Lind, Rolf I Skotheim, Ragnhild A Lothe, Manuel R Teixeira
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/35096269b807436484e8aab535a5939d
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