Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin

The mHsp60-mHsp10 chaperonin system forms alternating single and double ring complexes to assist protein folding, but the molecular details of this cycle are not fully understood. Here, the authors present cryoEM and crystal structures of key intermediates of the mHsp60-mHsp10 reaction cycle.

Guardado en:
Detalles Bibliográficos
Autores principales: Yacob Gomez-Llorente, Fady Jebara, Malay Patra, Radhika Malik, Shahar Nisemblat, Orna Chomsky-Hecht, Avital Parnas, Abdussalam Azem, Joel A. Hirsch, Iban Ubarretxena-Belandia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/350b4f4502ee4f4abafe17203699bcde
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares