Ulinastatin alleviates traumatic brain injury by reducing endothelin-1

Brain edema is one of the major causes of fatality and disability associated with injury and neurosurgical procedures. The goal of this study was to evaluate the effect of ulinastatin (UTI), a protease inhibitor, on astrocytes in a rat model of traumatic brain injury (TBI).

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Autores principales:	Liu Ting, Liao Xing-Zhi, Zhou Mai-Tao
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2020
Materias:	ulinastatin traumatic brain injury brain edema astrocyte endothelin-1 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/3510c6fa0bef4d15af73dadbc3254743
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spelling	oai:doaj.org-article:3510c6fa0bef4d15af73dadbc32547432021-12-05T14:11:05ZUlinastatin alleviates traumatic brain injury by reducing endothelin-12081-693610.1515/tnsci-2021-0001https://doaj.org/article/3510c6fa0bef4d15af73dadbc32547432020-12-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2021-0001https://doaj.org/toc/2081-6936Brain edema is one of the major causes of fatality and disability associated with injury and neurosurgical procedures. The goal of this study was to evaluate the effect of ulinastatin (UTI), a protease inhibitor, on astrocytes in a rat model of traumatic brain injury (TBI).Liu TingLiao Xing-ZhiZhou Mai-TaoDe Gruyterarticleulinastatintraumatic brain injurybrain edemaastrocyteendothelin-1Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 12, Iss 1, Pp 001-008 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	ulinastatin traumatic brain injury brain edema astrocyte endothelin-1 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	ulinastatin traumatic brain injury brain edema astrocyte endothelin-1 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Liu Ting Liao Xing-Zhi Zhou Mai-Tao Ulinastatin alleviates traumatic brain injury by reducing endothelin-1
description	Brain edema is one of the major causes of fatality and disability associated with injury and neurosurgical procedures. The goal of this study was to evaluate the effect of ulinastatin (UTI), a protease inhibitor, on astrocytes in a rat model of traumatic brain injury (TBI).
format	article
author	Liu Ting Liao Xing-Zhi Zhou Mai-Tao
author_facet	Liu Ting Liao Xing-Zhi Zhou Mai-Tao
author_sort	Liu Ting
title	Ulinastatin alleviates traumatic brain injury by reducing endothelin-1
title_short	Ulinastatin alleviates traumatic brain injury by reducing endothelin-1
title_full	Ulinastatin alleviates traumatic brain injury by reducing endothelin-1
title_fullStr	Ulinastatin alleviates traumatic brain injury by reducing endothelin-1
title_full_unstemmed	Ulinastatin alleviates traumatic brain injury by reducing endothelin-1
title_sort	ulinastatin alleviates traumatic brain injury by reducing endothelin-1
publisher	De Gruyter
publishDate	2020
url	https://doaj.org/article/3510c6fa0bef4d15af73dadbc3254743
work_keys_str_mv	AT liuting ulinastatinalleviatestraumaticbraininjurybyreducingendothelin1 AT liaoxingzhi ulinastatinalleviatestraumaticbraininjurybyreducingendothelin1 AT zhoumaitao ulinastatinalleviatestraumaticbraininjurybyreducingendothelin1
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Ulinastatin alleviates traumatic brain injury by reducing endothelin-1

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