Sorting at embryonic boundaries requires high heterotypic interfacial tension

The mechanisms that cause different cells to segregate into distinct tissues are unclear. Here the authors show in Xenopus that formation of a boundary between two tissues is driven by local tension along the interface rather than by global differences in adhesion or cortical contractility.

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Autores principales: Laura Canty, Eleyine Zarour, Leily Kashkooli, Paul François, François Fagotto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3525ae5918e84707aa7997aafe75f1f3
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