STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS

Blood levels of tumor necrosis factor-α (TNFα) and interferon γ (IFNγ) are shown to be increased in patients with rheumatoid arthritis, as compared to normal values. An increase of TNFα levels is shown to correlate with higher activity of inflammatory process, as well as with extra-articulate lesion...

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Autores principales: M. V. Pachkunova, T. G. Danilova, E. V. Feofanovа
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/3539a6106fe6440aae0a2edacba998a8
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spelling oai:doaj.org-article:3539a6106fe6440aae0a2edacba998a82021-11-18T08:03:44ZSTUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS1563-06252313-741X10.15789/1563-0625-2014-3-273-280https://doaj.org/article/3539a6106fe6440aae0a2edacba998a82014-08-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/693https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XBlood levels of tumor necrosis factor-α (TNFα) and interferon γ (IFNγ) are shown to be increased in patients with rheumatoid arthritis, as compared to normal values. An increase of TNFα levels is shown to correlate with higher activity of inflammatory process, as well as with extra-articulate lesions in patients. Concentration of IFNγ proved to be significantly connected with activity of inflammatory process, and at later terms of the disorder ( > 1 year). TNFα and IFNγ levels are interconnected with joint lesions and functional scores of patients with rheumatoid arthritis.M. V. PachkunovaT. G. DanilovaE. V. FeofanovаSPb RAACIarticlerheumatoid arthritiscytokinestumor necrosis factor-αinterferon-γImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 16, Iss 3, Pp 273-280 (2014)
institution DOAJ
collection DOAJ
language RU
topic rheumatoid arthritis
cytokines
tumor necrosis factor-α
interferon-γ
Immunologic diseases. Allergy
RC581-607
spellingShingle rheumatoid arthritis
cytokines
tumor necrosis factor-α
interferon-γ
Immunologic diseases. Allergy
RC581-607
M. V. Pachkunova
T. G. Danilova
E. V. Feofanovа
STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS
description Blood levels of tumor necrosis factor-α (TNFα) and interferon γ (IFNγ) are shown to be increased in patients with rheumatoid arthritis, as compared to normal values. An increase of TNFα levels is shown to correlate with higher activity of inflammatory process, as well as with extra-articulate lesions in patients. Concentration of IFNγ proved to be significantly connected with activity of inflammatory process, and at later terms of the disorder ( > 1 year). TNFα and IFNγ levels are interconnected with joint lesions and functional scores of patients with rheumatoid arthritis.
format article
author M. V. Pachkunova
T. G. Danilova
E. V. Feofanovа
author_facet M. V. Pachkunova
T. G. Danilova
E. V. Feofanovа
author_sort M. V. Pachkunova
title STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS
title_short STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS
title_full STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS
title_fullStr STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS
title_full_unstemmed STUDIES OF SEVERAL BLOOD CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: CLINICAL AND IMMUNOLOGAL INTERRRELATIONS
title_sort studies of several blood cytokines in patients with rheumatoid arthritis: clinical and immunologal interrrelations
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/3539a6106fe6440aae0a2edacba998a8
work_keys_str_mv AT mvpachkunova studiesofseveralbloodcytokinesinpatientswithrheumatoidarthritisclinicalandimmunologalinterrrelations
AT tgdanilova studiesofseveralbloodcytokinesinpatientswithrheumatoidarthritisclinicalandimmunologalinterrrelations
AT evfeofanova studiesofseveralbloodcytokinesinpatientswithrheumatoidarthritisclinicalandimmunologalinterrrelations
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