Inhibition of cancer stem cell like cells by a synthetic retinoid

Inhibition of cancer stem cell like cells by a synthetic retinoid

The discovery of efficient drugs is a main challenge in cancer therapy. Here, the authors report a synthetic retinoid, WYC-209 with anti-tumor and anti-metastatic activity mediated by the retinoic acid receptor signaling pathway.

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Autores principales: Junwei Chen, Xin Cao, Quanlin An, Yao Zhang, Ke Li, Wenting Yao, Fuchun Shi, Yanfang Pan, Qiong Jia, Wenwen Zhou, Fang Yang, Fuxiang Wei, Ning Wang, Biao Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/353ec738ae8144b197cbedc2ea9be408
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spelling oai:doaj.org-article:353ec738ae8144b197cbedc2ea9be4082021-12-02T17:31:13ZInhibition of cancer stem cell like cells by a synthetic retinoid10.1038/s41467-018-03877-72041-1723https://doaj.org/article/353ec738ae8144b197cbedc2ea9be4082018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03877-7https://doaj.org/toc/2041-1723The discovery of efficient drugs is a main challenge in cancer therapy. Here, the authors report a synthetic retinoid, WYC-209 with anti-tumor and anti-metastatic activity mediated by the retinoic acid receptor signaling pathway.Junwei ChenXin CaoQuanlin AnYao ZhangKe LiWenting YaoFuchun ShiYanfang PanQiong JiaWenwen ZhouFang YangFuxiang WeiNing WangBiao YuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Junwei Chen
Xin Cao
Quanlin An
Yao Zhang
Ke Li
Wenting Yao
Fuchun Shi
Yanfang Pan
Qiong Jia
Wenwen Zhou
Fang Yang
Fuxiang Wei
Ning Wang
Biao Yu
Inhibition of cancer stem cell like cells by a synthetic retinoid
description The discovery of efficient drugs is a main challenge in cancer therapy. Here, the authors report a synthetic retinoid, WYC-209 with anti-tumor and anti-metastatic activity mediated by the retinoic acid receptor signaling pathway.
format article
author Junwei Chen
Xin Cao
Quanlin An
Yao Zhang
Ke Li
Wenting Yao
Fuchun Shi
Yanfang Pan
Qiong Jia
Wenwen Zhou
Fang Yang
Fuxiang Wei
Ning Wang
Biao Yu
author_facet Junwei Chen
Xin Cao
Quanlin An
Yao Zhang
Ke Li
Wenting Yao
Fuchun Shi
Yanfang Pan
Qiong Jia
Wenwen Zhou
Fang Yang
Fuxiang Wei
Ning Wang
Biao Yu
author_sort Junwei Chen
title Inhibition of cancer stem cell like cells by a synthetic retinoid
title_short Inhibition of cancer stem cell like cells by a synthetic retinoid
title_full Inhibition of cancer stem cell like cells by a synthetic retinoid
title_fullStr Inhibition of cancer stem cell like cells by a synthetic retinoid
title_full_unstemmed Inhibition of cancer stem cell like cells by a synthetic retinoid
title_sort inhibition of cancer stem cell like cells by a synthetic retinoid
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/353ec738ae8144b197cbedc2ea9be408
work_keys_str_mv AT junweichen inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT xincao inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT quanlinan inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT yaozhang inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT keli inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT wentingyao inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT fuchunshi inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT yanfangpan inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT qiongjia inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT wenwenzhou inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT fangyang inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT fuxiangwei inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT ningwang inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
AT biaoyu inhibitionofcancerstemcelllikecellsbyasyntheticretinoid
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