GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

Steroidal glycoalkaloids (SGAs) accumulate in solanaceous plants and contribute to plant defence but are toxic to humans. Here the authors show that the GAME9 transcription factor is a regulator of the SGA biosynthetic pathways providing a potential way to manipulate SGA levels in crops.

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Detalles Bibliográficos
Autores principales:	Pablo D. Cárdenas, Prashant D. Sonawane, Jacob Pollier, Robin Vanden Bossche, Veena Dewangan, Efrat Weithorn, Lior Tal, Sagit Meir, Ilana Rogachev, Sergey Malitsky, Ashok P. Giri, Alain Goossens, Saul Burdman, Asaph Aharoni
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/35438c54c52742e3bf9306b23b1ce178
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spelling	oai:doaj.org-article:35438c54c52742e3bf9306b23b1ce1782021-12-02T15:34:10ZGAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway10.1038/ncomms106542041-1723https://doaj.org/article/35438c54c52742e3bf9306b23b1ce1782016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10654https://doaj.org/toc/2041-1723Steroidal glycoalkaloids (SGAs) accumulate in solanaceous plants and contribute to plant defence but are toxic to humans. Here the authors show that the GAME9 transcription factor is a regulator of the SGA biosynthetic pathways providing a potential way to manipulate SGA levels in crops.Pablo D. CárdenasPrashant D. SonawaneJacob PollierRobin Vanden BosscheVeena DewanganEfrat WeithornLior TalSagit MeirIlana RogachevSergey MalitskyAshok P. GiriAlain GoossensSaul BurdmanAsaph AharoniNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pablo D. Cárdenas Prashant D. Sonawane Jacob Pollier Robin Vanden Bossche Veena Dewangan Efrat Weithorn Lior Tal Sagit Meir Ilana Rogachev Sergey Malitsky Ashok P. Giri Alain Goossens Saul Burdman Asaph Aharoni GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
description	Steroidal glycoalkaloids (SGAs) accumulate in solanaceous plants and contribute to plant defence but are toxic to humans. Here the authors show that the GAME9 transcription factor is a regulator of the SGA biosynthetic pathways providing a potential way to manipulate SGA levels in crops.
format	article
author	Pablo D. Cárdenas Prashant D. Sonawane Jacob Pollier Robin Vanden Bossche Veena Dewangan Efrat Weithorn Lior Tal Sagit Meir Ilana Rogachev Sergey Malitsky Ashok P. Giri Alain Goossens Saul Burdman Asaph Aharoni
author_facet	Pablo D. Cárdenas Prashant D. Sonawane Jacob Pollier Robin Vanden Bossche Veena Dewangan Efrat Weithorn Lior Tal Sagit Meir Ilana Rogachev Sergey Malitsky Ashok P. Giri Alain Goossens Saul Burdman Asaph Aharoni
author_sort	Pablo D. Cárdenas
title	GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
title_short	GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
title_full	GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
title_fullStr	GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
title_full_unstemmed	GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
title_sort	game9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/35438c54c52742e3bf9306b23b1ce178
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GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

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