Quantifying the benefit of a proteome reserve in fluctuating environments

Fast-growing bacteria produce many proteins in excess of what seems optimal for exponential growth. Here, the authors present a mathematical model and experimental evidence supporting that this overexpression serves as a strategic reserve to quickly meet demand upon sudden improvement in growth cond...

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Autores principales:	Matteo Mori, Severin Schink, David W. Erickson, Ulrich Gerland, Terence Hwa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3544e922e215469b80235c1a59ad032b
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spelling	oai:doaj.org-article:3544e922e215469b80235c1a59ad032b2021-12-02T14:40:36ZQuantifying the benefit of a proteome reserve in fluctuating environments10.1038/s41467-017-01242-82041-1723https://doaj.org/article/3544e922e215469b80235c1a59ad032b2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01242-8https://doaj.org/toc/2041-1723Fast-growing bacteria produce many proteins in excess of what seems optimal for exponential growth. Here, the authors present a mathematical model and experimental evidence supporting that this overexpression serves as a strategic reserve to quickly meet demand upon sudden improvement in growth conditions.Matteo MoriSeverin SchinkDavid W. EricksonUlrich GerlandTerence HwaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matteo Mori Severin Schink David W. Erickson Ulrich Gerland Terence Hwa Quantifying the benefit of a proteome reserve in fluctuating environments
description	Fast-growing bacteria produce many proteins in excess of what seems optimal for exponential growth. Here, the authors present a mathematical model and experimental evidence supporting that this overexpression serves as a strategic reserve to quickly meet demand upon sudden improvement in growth conditions.
format	article
author	Matteo Mori Severin Schink David W. Erickson Ulrich Gerland Terence Hwa
author_facet	Matteo Mori Severin Schink David W. Erickson Ulrich Gerland Terence Hwa
author_sort	Matteo Mori
title	Quantifying the benefit of a proteome reserve in fluctuating environments
title_short	Quantifying the benefit of a proteome reserve in fluctuating environments
title_full	Quantifying the benefit of a proteome reserve in fluctuating environments
title_fullStr	Quantifying the benefit of a proteome reserve in fluctuating environments
title_full_unstemmed	Quantifying the benefit of a proteome reserve in fluctuating environments
title_sort	quantifying the benefit of a proteome reserve in fluctuating environments
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3544e922e215469b80235c1a59ad032b
work_keys_str_mv	AT matteomori quantifyingthebenefitofaproteomereserveinfluctuatingenvironments AT severinschink quantifyingthebenefitofaproteomereserveinfluctuatingenvironments AT davidwerickson quantifyingthebenefitofaproteomereserveinfluctuatingenvironments AT ulrichgerland quantifyingthebenefitofaproteomereserveinfluctuatingenvironments AT terencehwa quantifyingthebenefitofaproteomereserveinfluctuatingenvironments
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Quantifying the benefit of a proteome reserve in fluctuating environments

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