Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

Metastatic cells can mimic many of the phenotypic behaviors of embryonic cells. Here, the authors generate a melanoblast-specific transcriptome using a genetically engineered mouse model and identify KDELR3 as a pro-metastasis gene in melanoma.

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Detalles Bibliográficos
Autores principales:	Kerrie L. Marie, Antonella Sassano, Howard H. Yang, Aleksandra M. Michalowski, Helen T. Michael, Theresa Guo, Yien Che Tsai, Allan M. Weissman, Maxwell P. Lee, Lisa M. Jenkins, M. Raza Zaidi, Eva Pérez-Guijarro, Chi-Ping Day, Kris Ylaya, Stephen M. Hewitt, Nimit L. Patel, Heinz Arnheiter, Sean Davis, Paul S. Meltzer, Glenn Merlino, Pravin J. Mishra
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/35727847607f4f45b98d5dc601c357f5
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spelling	oai:doaj.org-article:35727847607f4f45b98d5dc601c357f52021-12-02T15:37:15ZMelanoblast transcriptome analysis reveals pathways promoting melanoma metastasis10.1038/s41467-019-14085-22041-1723https://doaj.org/article/35727847607f4f45b98d5dc601c357f52020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14085-2https://doaj.org/toc/2041-1723Metastatic cells can mimic many of the phenotypic behaviors of embryonic cells. Here, the authors generate a melanoblast-specific transcriptome using a genetically engineered mouse model and identify KDELR3 as a pro-metastasis gene in melanoma.Kerrie L. MarieAntonella SassanoHoward H. YangAleksandra M. MichalowskiHelen T. MichaelTheresa GuoYien Che TsaiAllan M. WeissmanMaxwell P. LeeLisa M. JenkinsM. Raza ZaidiEva Pérez-GuijarroChi-Ping DayKris YlayaStephen M. HewittNimit L. PatelHeinz ArnheiterSean DavisPaul S. MeltzerGlenn MerlinoPravin J. MishraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kerrie L. Marie Antonella Sassano Howard H. Yang Aleksandra M. Michalowski Helen T. Michael Theresa Guo Yien Che Tsai Allan M. Weissman Maxwell P. Lee Lisa M. Jenkins M. Raza Zaidi Eva Pérez-Guijarro Chi-Ping Day Kris Ylaya Stephen M. Hewitt Nimit L. Patel Heinz Arnheiter Sean Davis Paul S. Meltzer Glenn Merlino Pravin J. Mishra Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
description	Metastatic cells can mimic many of the phenotypic behaviors of embryonic cells. Here, the authors generate a melanoblast-specific transcriptome using a genetically engineered mouse model and identify KDELR3 as a pro-metastasis gene in melanoma.
format	article
author	Kerrie L. Marie Antonella Sassano Howard H. Yang Aleksandra M. Michalowski Helen T. Michael Theresa Guo Yien Che Tsai Allan M. Weissman Maxwell P. Lee Lisa M. Jenkins M. Raza Zaidi Eva Pérez-Guijarro Chi-Ping Day Kris Ylaya Stephen M. Hewitt Nimit L. Patel Heinz Arnheiter Sean Davis Paul S. Meltzer Glenn Merlino Pravin J. Mishra
author_facet	Kerrie L. Marie Antonella Sassano Howard H. Yang Aleksandra M. Michalowski Helen T. Michael Theresa Guo Yien Che Tsai Allan M. Weissman Maxwell P. Lee Lisa M. Jenkins M. Raza Zaidi Eva Pérez-Guijarro Chi-Ping Day Kris Ylaya Stephen M. Hewitt Nimit L. Patel Heinz Arnheiter Sean Davis Paul S. Meltzer Glenn Merlino Pravin J. Mishra
author_sort	Kerrie L. Marie
title	Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
title_short	Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
title_full	Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
title_fullStr	Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
title_full_unstemmed	Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
title_sort	melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/35727847607f4f45b98d5dc601c357f5
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Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

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