Early-Stage <italic toggle="yes">Staphylococcus aureus</italic> Bloodstream Infection Causes Changes in the Concentrations of Lipoproteins and Acute-Phase Proteins and Is Associated with Low Antibody Titers against Bacterial Virulence Factors

Early-Stage <italic toggle="yes">Staphylococcus aureus</italic> Bloodstream Infection Causes Changes in the Concentrations of Lipoproteins and Acute-Phase Proteins and Is Associated with Low Antibody Titers against Bacterial Virulence Factors

ABSTRACT Systemic and quantitative investigations of human plasma proteins (proteomics) and Staphylococcus aureus-specific antibodies (immunoproteomics) provide complementary information and hold promise for the discovery of biomarkers in Staphylococcus aureus bloodstream infection (SABSI). Usually,...

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Bibliographic Details
Main Authors: Stephan Michalik, Nandakumar Sundaramoorthy, Annette Murr, Maren Depke, Uwe Völker, Barbara M. Bröker, Hege Vangstein Aamot, Frank Schmidt
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
DIA mass spectrometry
Staphylococcus aureus
biomarker
bloodstream infections
immunoproteomics
proteomics
Microbiology
QR1-502
Online Access:https://doaj.org/article/3572e81656174a26a0de9cae2d5fb482
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