Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry

Introduction: Periprocedural stroke represents a rare but serious complication of cardiac catheterization. Pooled data from randomized trials evaluating the risk of stroke following cardiac catheterization via transradial versus transfemoral access showed no difference. On the other hand, a signific...

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Autores principales: Jan Matějka, Ivo Varvařovský, Jan Tužil, Tomáš Doležal, Martin Bobak, Jan Pospíchal, Petr Geier, Jiří Vondrák, Karel Bláha, Jan Málek, Alena Staňková, Juraj Bujdák, Vladimír Rozsíval, Vojtěch Novotný, Tomáš Lazarák, Milan Plíva, Jan Večeřa, Petr Vojtíšek
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Publicado: Karger Publishers 2021
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spelling oai:doaj.org-article:357527be3b5a4fd6a15acb167704a76c2021-11-25T07:47:20ZAccession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry1664-545610.1159/000519539https://doaj.org/article/357527be3b5a4fd6a15acb167704a76c2021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/519539https://doaj.org/toc/1664-5456Introduction: Periprocedural stroke represents a rare but serious complication of cardiac catheterization. Pooled data from randomized trials evaluating the risk of stroke following cardiac catheterization via transradial versus transfemoral access showed no difference. On the other hand, a significant difference in stroke rates favoring transradial access was found in a recent meta-analysis of observational studies. Our aim was to determine if there is a difference in stroke risk after transradial versus transfemoral catheterization within a contemporary real-world registry. Methods: Data from 14,139 patients included in a single-center prospective registry between 2009 and 2016 were used to determine the odds of periprocedural transient ischemic attack (TIA) and stroke for radial versus femoral catheterization via multivariate logistic regression with Firth’s correction. Results: A total of 10,931 patients underwent transradial and 3,208 underwent transfemoral catheterization. Periprocedural TIA/stroke occurred in 41 (0.29%) patients. Age was the only significant predictor of TIA/stroke in multivariate analysis, with each additional year representing an odds ratio (OR) = 1.09 (CI 1.05–1.13, p < 0.000). The choice of accession site had no impact on the risk of periprocedural TIA/stroke (OR = 0.81; CI 0.38–1.72, p = 0.577). Conclusion: Observational data from a large prospective registry indicate that accession site has no influence on the risk of periprocedural TIA/stroke after cardiac catheterization.Jan MatějkaIvo VarvařovskýJan TužilTomáš DoležalMartin BobakJan PospíchalPetr GeierJiří VondrákKarel BláhaJan MálekAlena StaňkováJuraj BujdákVladimír RozsívalVojtěch NovotnýTomáš LazarákMilan PlívaJan VečeřaPetr VojtíšekKarger Publishersarticlestroketransient ischemic attackcardiac catheterizationfemoral accessradial accessDiseases of the circulatory (Cardiovascular) systemRC666-701ENCerebrovascular Diseases Extra, Vol 11, Iss 3, Pp 122-130 (2021)
institution DOAJ
collection DOAJ
language EN
topic stroke
transient ischemic attack
cardiac catheterization
femoral access
radial access
Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle stroke
transient ischemic attack
cardiac catheterization
femoral access
radial access
Diseases of the circulatory (Cardiovascular) system
RC666-701
Jan Matějka
Ivo Varvařovský
Jan Tužil
Tomáš Doležal
Martin Bobak
Jan Pospíchal
Petr Geier
Jiří Vondrák
Karel Bláha
Jan Málek
Alena Staňková
Juraj Bujdák
Vladimír Rozsíval
Vojtěch Novotný
Tomáš Lazarák
Milan Plíva
Jan Večeřa
Petr Vojtíšek
Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry
description Introduction: Periprocedural stroke represents a rare but serious complication of cardiac catheterization. Pooled data from randomized trials evaluating the risk of stroke following cardiac catheterization via transradial versus transfemoral access showed no difference. On the other hand, a significant difference in stroke rates favoring transradial access was found in a recent meta-analysis of observational studies. Our aim was to determine if there is a difference in stroke risk after transradial versus transfemoral catheterization within a contemporary real-world registry. Methods: Data from 14,139 patients included in a single-center prospective registry between 2009 and 2016 were used to determine the odds of periprocedural transient ischemic attack (TIA) and stroke for radial versus femoral catheterization via multivariate logistic regression with Firth’s correction. Results: A total of 10,931 patients underwent transradial and 3,208 underwent transfemoral catheterization. Periprocedural TIA/stroke occurred in 41 (0.29%) patients. Age was the only significant predictor of TIA/stroke in multivariate analysis, with each additional year representing an odds ratio (OR) = 1.09 (CI 1.05–1.13, p < 0.000). The choice of accession site had no impact on the risk of periprocedural TIA/stroke (OR = 0.81; CI 0.38–1.72, p = 0.577). Conclusion: Observational data from a large prospective registry indicate that accession site has no influence on the risk of periprocedural TIA/stroke after cardiac catheterization.
format article
author Jan Matějka
Ivo Varvařovský
Jan Tužil
Tomáš Doležal
Martin Bobak
Jan Pospíchal
Petr Geier
Jiří Vondrák
Karel Bláha
Jan Málek
Alena Staňková
Juraj Bujdák
Vladimír Rozsíval
Vojtěch Novotný
Tomáš Lazarák
Milan Plíva
Jan Večeřa
Petr Vojtíšek
author_facet Jan Matějka
Ivo Varvařovský
Jan Tužil
Tomáš Doležal
Martin Bobak
Jan Pospíchal
Petr Geier
Jiří Vondrák
Karel Bláha
Jan Málek
Alena Staňková
Juraj Bujdák
Vladimír Rozsíval
Vojtěch Novotný
Tomáš Lazarák
Milan Plíva
Jan Večeřa
Petr Vojtíšek
author_sort Jan Matějka
title Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry
title_short Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry
title_full Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry
title_fullStr Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry
title_full_unstemmed Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry
title_sort accession site does not influence the risk of stroke after diagnostic coronary angiography or intervention: results from a large prospective registry
publisher Karger Publishers
publishDate 2021
url https://doaj.org/article/357527be3b5a4fd6a15acb167704a76c
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