Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor

Type IV pili (T4P) are retractile appendages used by bacteria for DNA uptake and other purposes. T4P extension is thought to occur through the action of a single motor protein, PilB. Here, Ellison et al. show that T4P synthesis in Acinetobacter baylyi depends not only on PilB but also on an addition...

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Auteurs principaux: Courtney K. Ellison, Triana N. Dalia, Catherine A. Klancher, Joshua W. Shaevitz, Zemer Gitai, Ankur B. Dalia
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/3583dbdef1c547f08c1c0c160d87bd4c
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spelling oai:doaj.org-article:3583dbdef1c547f08c1c0c160d87bd4c2021-12-02T17:40:27ZAcinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor10.1038/s41467-021-24124-62041-1723https://doaj.org/article/3583dbdef1c547f08c1c0c160d87bd4c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24124-6https://doaj.org/toc/2041-1723Type IV pili (T4P) are retractile appendages used by bacteria for DNA uptake and other purposes. T4P extension is thought to occur through the action of a single motor protein, PilB. Here, Ellison et al. show that T4P synthesis in Acinetobacter baylyi depends not only on PilB but also on an additional, distinct motor, TfpB.Courtney K. EllisonTriana N. DaliaCatherine A. KlancherJoshua W. ShaevitzZemer GitaiAnkur B. DaliaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Courtney K. Ellison
Triana N. Dalia
Catherine A. Klancher
Joshua W. Shaevitz
Zemer Gitai
Ankur B. Dalia
Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor
description Type IV pili (T4P) are retractile appendages used by bacteria for DNA uptake and other purposes. T4P extension is thought to occur through the action of a single motor protein, PilB. Here, Ellison et al. show that T4P synthesis in Acinetobacter baylyi depends not only on PilB but also on an additional, distinct motor, TfpB.
format article
author Courtney K. Ellison
Triana N. Dalia
Catherine A. Klancher
Joshua W. Shaevitz
Zemer Gitai
Ankur B. Dalia
author_facet Courtney K. Ellison
Triana N. Dalia
Catherine A. Klancher
Joshua W. Shaevitz
Zemer Gitai
Ankur B. Dalia
author_sort Courtney K. Ellison
title Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor
title_short Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor
title_full Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor
title_fullStr Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor
title_full_unstemmed Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor
title_sort acinetobacter baylyi regulates type iv pilus synthesis by employing two extension motors and a motor protein inhibitor
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3583dbdef1c547f08c1c0c160d87bd4c
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AT trianandalia acinetobacterbaylyiregulatestypeivpilussynthesisbyemployingtwoextensionmotorsandamotorproteininhibitor
AT catherineaklancher acinetobacterbaylyiregulatestypeivpilussynthesisbyemployingtwoextensionmotorsandamotorproteininhibitor
AT joshuawshaevitz acinetobacterbaylyiregulatestypeivpilussynthesisbyemployingtwoextensionmotorsandamotorproteininhibitor
AT zemergitai acinetobacterbaylyiregulatestypeivpilussynthesisbyemployingtwoextensionmotorsandamotorproteininhibitor
AT ankurbdalia acinetobacterbaylyiregulatestypeivpilussynthesisbyemployingtwoextensionmotorsandamotorproteininhibitor
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