The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet
Abstract Obesity and diabetes increase the risk of arrhythmia and sudden cardiac death. However, the molecular mechanisms of arrhythmia caused by metabolic abnormalities are not well understood. We hypothesized that mitochondrial dysfunction caused by high fat diet (HFD) promotes ventricular arrhyth...
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Main Authors: | Leroy C. Joseph, Michael V. Reyes, Edwin A. Homan, Blake Gowen, Uma Mahesh R. Avula, Chris N. Goulbourne, Elaine Y. Wan, John W. Elrod, John P. Morrow |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/3583dde928184485acfbb8b933a21ddc |
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