The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet

The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet

Abstract Obesity and diabetes increase the risk of arrhythmia and sudden cardiac death. However, the molecular mechanisms of arrhythmia caused by metabolic abnormalities are not well understood. We hypothesized that mitochondrial dysfunction caused by high fat diet (HFD) promotes ventricular arrhyth...

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Autores principales: Leroy C. Joseph, Michael V. Reyes, Edwin A. Homan, Blake Gowen, Uma Mahesh R. Avula, Chris N. Goulbourne, Elaine Y. Wan, John W. Elrod, John P. Morrow
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3583dde928184485acfbb8b933a21ddc
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