Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

Viral infection transiently depletes T regulatory cells (Treg). Here the authors identify a compensatory induced Treg population, which is required to rapidly replenish the Treg niche and suppress microbiota-driven, virus-induced colitis.

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Autores principales: Michelle Schorer, Katharina Lambert, Nikolas Rakebrandt, Felix Rost, Kung-Chi Kao, Alexander Yermanos, Roman Spörri, Josua Oderbolz, Miro E. Raeber, Christian W. Keller, Jan D. Lünemann, Gerhard Rogler, Onur Boyman, Annette Oxenius, Nicole Joller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/358d973756854a01949a43086610135a
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spelling oai:doaj.org-article:358d973756854a01949a43086610135a2021-12-02T14:41:15ZRapid expansion of Treg cells protects from collateral colitis following a viral trigger10.1038/s41467-020-15309-62041-1723https://doaj.org/article/358d973756854a01949a43086610135a2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15309-6https://doaj.org/toc/2041-1723Viral infection transiently depletes T regulatory cells (Treg). Here the authors identify a compensatory induced Treg population, which is required to rapidly replenish the Treg niche and suppress microbiota-driven, virus-induced colitis.Michelle SchorerKatharina LambertNikolas RakebrandtFelix RostKung-Chi KaoAlexander YermanosRoman SpörriJosua OderbolzMiro E. RaeberChristian W. KellerJan D. LünemannGerhard RoglerOnur BoymanAnnette OxeniusNicole JollerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Michelle Schorer
Katharina Lambert
Nikolas Rakebrandt
Felix Rost
Kung-Chi Kao
Alexander Yermanos
Roman Spörri
Josua Oderbolz
Miro E. Raeber
Christian W. Keller
Jan D. Lünemann
Gerhard Rogler
Onur Boyman
Annette Oxenius
Nicole Joller
Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
description Viral infection transiently depletes T regulatory cells (Treg). Here the authors identify a compensatory induced Treg population, which is required to rapidly replenish the Treg niche and suppress microbiota-driven, virus-induced colitis.
format article
author Michelle Schorer
Katharina Lambert
Nikolas Rakebrandt
Felix Rost
Kung-Chi Kao
Alexander Yermanos
Roman Spörri
Josua Oderbolz
Miro E. Raeber
Christian W. Keller
Jan D. Lünemann
Gerhard Rogler
Onur Boyman
Annette Oxenius
Nicole Joller
author_facet Michelle Schorer
Katharina Lambert
Nikolas Rakebrandt
Felix Rost
Kung-Chi Kao
Alexander Yermanos
Roman Spörri
Josua Oderbolz
Miro E. Raeber
Christian W. Keller
Jan D. Lünemann
Gerhard Rogler
Onur Boyman
Annette Oxenius
Nicole Joller
author_sort Michelle Schorer
title Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
title_short Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
title_full Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
title_fullStr Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
title_full_unstemmed Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
title_sort rapid expansion of treg cells protects from collateral colitis following a viral trigger
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/358d973756854a01949a43086610135a
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